Et profilbilde

Professor
Svein Bjelland { "honorific-suffix": "Professor", "fn": "Svein Bjelland", "tel": "Telephone: +47 51831884", "email": "svein.bjelland@uis.no" }

Faculty Faculty of Science and Technology
Department Department of Chemistry and Bioscience
Room KE E-528

Research fields

Selected publications

Research in progress

Work experience

Scientific publications (from Cristin)

  • Alexeeva, Marina; Guragain, Prashanna; Tesfahun, Almaz Nigatu; Tomkuvienė, Miglė; Arshad, Aysha; Gerasimaitė, Rūta; Rukšėnaitė, Audronė; Urbanavičiūtė, Giedrė; Bjørås, Magnar; Lærdahl, Jon Kristen; Klungland, Arne; Klimašauskas, Saulius; Bjelland, Svein (2018). Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins. Philosophical Transactions of the Royal Society of London. Biological Sciences. ISSN 0962-8436. Volume 373. Booklet 1748. DOI: 10.1098/rstb.2017.0337.
  • Moen, Marivi; Knævelsrud, Ingeborg; Haugland, Gyri Teien; Grøsvik, Kristin; Birkeland, Nils-Kåre; Klungland, Arne; Bjelland, Svein (2011). Uracil-DNA Glycosylase of Thermoplasma acidophilum Directs Long-Patch Base Excision Repair, Which Is Promoted by Deoxynucleoside Triphosphates and ATP/ADP, into Short-Patch Repair. Journal of Bacteriology. ISSN 0021-9193. Volume 193. Booklet 17. p. 4495-4508. DOI: 10.1128/JB.00233-11.
  • Knævelsrud, Ingeborg; Moen, Marivi; Grøsvik, Kristin; Haugland, Gyri Teien; Birkeland, Nils-Kåre; Klungland, Arne; Leiros, Ingar; Bjelland, Svein (2010). The Hyperthermophilic Euryarchaeon Archaeoglobus fulgidus Repairs Uracil by Single-Nucleotide Replacement. Journal of Bacteriology. ISSN 0021-9193. Volume 192. Booklet 21. p. 5755-5766. DOI: 10.1128/JB.00135-10.
  • Knævelsrud, I.; Slupphaug, Geir; Leiros, Ingar; Matsuda, A.; Ruoff, Peter; Bjelland, Svein (2009). Opposite-base dependent excision of 5-formyluracil from DNA by hSMUG1. International Journal of Radiation Biology. ISSN 0955-3002. Volume 85. Booklet 5. p. 413-420.
  • Ringvoll, Jeanette; Moen, Marivi N.; Nordstrand, Line M.; Meira, Lisiane B.; Pang, Bo; Bekkelund, Anders; Dedon, Peter C.; Bjelland, Svein; Samson, Leona D.; Falnes, Pål Ø.; Klungland, Arne (2008). AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA. Cancer Research. ISSN 0008-5472. Volume 68. Booklet 11. p. 4142-4149.
  • Klungland, Arne; Bjelland, Svein (2007). Oxidative damage to purines in DNA: Role of mammalian Ogg1. DNA Repair. ISSN 1568-7864. Volume 6.
  • Leiros, Ingar; Nabong, Marivi P.; Grøsvik, Kristin; Ringvoll, Jeanette; Haugland, GT; Uldal, Lene; Reite, Karen; Olsbu, Inger K.; Knævelsrud, I.; Moe, Elin; Andersen, Ole A.; Birkeland, Nils-Kåre; Ruoff, Peter; Klungland, Arne; Bjelland, Svein (2007). Structural basis for enzymatic excision of N-1-methyladenine and N-3-methylcytosine from DNA. EMBO Journal. ISSN 0261-4189. Volume 26.
  • Bjelland, Svein; Seeberg, E. (2003). Mutagenicity, toxicity and repair of DNA base damage induced by oxidation. Mutation research. Reviews in mutation research. ISSN 1383-5742. Volume 531. p. 37-80.
  • Birkeland, Nils-Kåre; Ånensen, Hilde; Knævelsrud, Ingeborg; Kristoffersen, Wenche; Bjørås, M.; Robb, F.T.; Klungland, Arne; Bjelland, Svein (2002). Methylpurine DNA glycosylase of the hyperthermophilic archaeon Archaeoglobus fulgidus. Biochemistry. ISSN 1520-4995. Volume 41. p. 12697-12705.
  • Bjelland, S.; Knævelsrud, I.; Seeberg, E. (2001). Cellular effects of 5-formyluracil in DNA (Review). Mutation research. Reviews in mutation research. ISSN 1383-5742. Volume 486. p. 147-154.
  • Bjelland, Svein; Klungland, Arne; Paulsen, R.; Rolseth, V.; Yamada, Y.; Ueno, Y.; Wiik, P.; Matsuda, A.; Seeberg, E. (2001). 5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism. Toxicology Letters. ISSN 0378-4274. Volume 119. p. 71-78.
  • Bjelland, Svein; Ånensen, Hilde; Knævelsrud, Ingeborg; Seeberg, E. (2001). Cellular effects of 5-formyluracil in DNA. Mutation research. Reviews in mutation research. ISSN 1383-5742. Volume 486. p. 147-154.
  • Knævelsrud, I.; Ruoff, Peter; ukjent-for-m012243, ukjent-for-m012243; Klungland, A.; Birkeland, N.-K. (2001). Excision of uracil from DNA by the hyperthermophilic Afung protein is dependent on the opposite base and stimulated by heat-induced transition to a more open structure. Excision of uracil from DNA by the hyperthermophilic Afung protein is dependent on the opposite base and stimulated by heat-induced transition to a more open structure. Volume 487. p. 173-190.
  • ukjent-for-m012243, ukjent-for-m012243; Provan, Fiona; Lian, A.T.; Reinertsen, S.-H.H.S; Ueno, Y.; Matsuda, A.; Seeberg, E. (2001). Mutations induced by 5-formyl-2´-deoxyuridine in Escherichia coli include base substitutions that can arise from mispairs of 5-formyluracil with guanine, cytosine and thymine. Mutation research. Reviews in mutation research. ISSN 1383-5742. Volume 476. p. 99-107.
  • Bjelland, Svein; Seeberg, E. (1996). Different efficiencies of the Tag and AlkA DNA glycosylases from Escherichia coli in the removal of 3-methyladenine from single-stranded DNA. FEBS Letters. ISSN 0014-5793. Volume 397. p. 127-129.
  • Bjelland, Svein; Birkeland, N.-K.; Benneche, T.; Volden, G.; Seeberg, E. (1994). DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the AlkA enzyme in Escherichia coli. Journal of Biological Chemistry. ISSN 0021-9258. Volume 269. p. 30489-30495.
  • Bjørås, M.; Berdal, K.G.; Bjelland, Svein; Seeberg, E. (1990). Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene. EMBO Journal. ISSN 0261-4189. Volume 9. p. 4563-4568.
  • Bjelland, Svein (1997). Base excision repair of DNA damage induced by alkylating and oxidative agents. Universitetet i Oslo.
  • Alexeeva, Marina; Moen, Marivi Nabong; Xu, Xiang Ming; Rasmussen, Anette; Kirpekar, Finn; Klungland, Arne; Bjelland, Svein (2017). hSMUG1 is a bi-functional DNA glycosylase. Norwegian Biochemical Society; 2017-01-19 - 2017-01-22.
  • Tesfahun, Almaz Nigatu; Klungland, Arne; Klimasauskas, Saulius; Bjelland, Svein (2017). Repair of double methylated bases in DNA. Norwegian Biochemical Society; 2017-01-19 - 2017-01-22.
  • Alexeeva, Maria; Tesfahun, Almaz Nigatu; Bjelland, Svein (2016). DNA uracil excision includes strand incision by hUNG and hSMUG1. Vilnius University;
  • Alexeeva, Marina; Moen, Marivi Nabong; Xu, Xiang Ming; Rasmussen, Anette; Kirpekar, Finn; Klungland, Arne; Bjelland, Svein (2016). hSMUG1-catalysed uracil-DNA strand incision. FEBS; 2016-10-03 - 2016-10-08.
  • Alexeeva, Marina; Moen, Marivi Nabong; Xu, Xiang Ming; Rasmussen, Anette; Kirpekar, Finn; Klungland, Arne; Bjelland, Svein (2016). hSMUG1-catalysed uracil-DNA strand incision. 2016-08-25 - 2016-08-28.
  • Tesfahun, Almaz Nigatu; Alexeeva, Marina; Bjelland, Svein (2016). Repair of double methylated bases in DNA. Vilnius University;
  • Tesfahun, Almaz Nigatu; Klungland, Arne; Klimasauskas, Saulius; Bjelland, Svein (2016). Repair of double methylated bases in DNA. 7th Annual BioStruct Conference; 2016-08-25 - 2016-08-28.
  • Bjelland, Svein (2015). "The king of base excision repair" fikk omsider Nobelprisen i år. Norsk Kjemisk Selskap; 2015-12-11.
  • Knævelsrud, Ingeborg; Kazazic, Sabina; Birkeland, Nils-Kåre; Bjelland, Svein (2014). The pH optimum of native uracil-DNA glycosylase of Archaeoglobus fulgidus compared to recombinant enzyme indicates adaption to cytosolic pH.
  • Muruzábal-Lecumberri, Izaskun; Grøsvik, Kristin; Matsuda, Akira; Bjelland, Svein (2014). Alleviation and promotion of damage-specific mutation induction in Escherichia coli are dependent on the uvrA gene. 2014-11-12 - 2014-11-16.
  • Bjelland, Svein (2010). Base excision repair in euryarchaeons. 2010-05-22.
  • Bjelland, Svein (2010). Tungvint kreftbehandling.
  • Leiros, Ingar; Nabong, Marivi P.; Haugland, GT; Ringvoll, Jeanette; Grøsvik, K; Grøsvik, K; Moe, Elin; Knævelsrud, I.; Knævelsrud, I.; Reite, Karen; Andersen, Ole A.; Birkeland, Nils-Kåre; Klungland, Arne; Bjelland, Svein; Bjelland, Svein (2006). Excision of 1-methyladenine and 3-methylcytosine from DNA by AfAlkA of Archaeoglobus fulgidus. 2006-05-30 - 2006-06-05.
  • Leiros, Ingar; Nabong, Marivi P.; Haugland, Gyri Teien; Ringvoll, Jeanette; Grøsvik, Kristin; Moe, Elin; Knævelsrud, Ingeborg; Reite, Karen; Andersen, Ole Andreas; Birkeland, Nils-Kåre; Klungland, Arne; Bjelland, Svein (2006). Excision of 1-methyladenine and 3-methylcytosine from DNA by AfAlkA of Archaeoglobus fulgidus.. 2006-05-28 - 2006-06-02.
  • Bjelland, Svein; Knævelsrud, Ingeborg; Haugland, Gyri Teien; Klungland, Arne; Birkeland, Nils-Kåre (2005). Excision of dUMP from DNA by the hyperthermophilic archaeon Archaeoglobus fulgidus.. International symposium on Extremophils and Their Applicatio; 2005-11-29 - 2005-12-02.
  • Knævelsrud, I.; Klungland, A.; Birkeland, N.-K.; Bjelland, Svein (2005). Excision of dUMP from DNA by the hyperthermophilic archaeon Archaeoglobus fulgidus. 2005-11-30 - 2005-12-02.
  • Knævelsrud, I.; Haugland, GT; Birkeland, N.-K.; Bjelland, Svein (2004). Excision of dUMP from DNA by the hyperthermophilic archaeon Archaeoglobus fulgidus. 2004-11-14 - 2004-11-20.
  • Knævelsrud, Ingeborg; Haugland, Gyri Teien; Birkeland, Nils-Kåre; Bjelland, Svein (2004). Excision of dUMP from DNA by the hyperthermophilic archaeon Archaeoglobus fulgidus.. American Society for Microbiology; 2004-11-14 - 2004-11-20.
  • Knævelsrud, Ingeborg; Birkeland, Nils-Kåre; Bjelland, Svein (2003). Afung represents the principal uracil DNA glycosylase enzyme present in the hyperthermophilic archaeon Archaeoglobus fu. 2003-09-15 - 2003-09-19.
  • Birkeland, Nils-Kåre; Ånensen, Hilde; Kristoffersen, Wenche; Knævelsrud, Ingeborg; Bjørås, M.; Klungland, Arne; Robb, F.T.; Bjelland, Svein (2002). Cold-active methylpurine DNA glycosylase of the hyperthermophilic archaeon Archaeoglobus fulgidus. 2002-09-22 - 2002-09-26.
  • Knævelsrud, Ingeborg; Bjelland, Svein; Birkeland, Nils-Kåre (2001). Uracil-DNA glycosylase from the hyperthermophilic archaeon Archaeoglobus fulgidus.
  • Bjelland, Svein; Klungland, A.; Provan, Fiona; Lian, A. T.; Ånensen, H.; Selmer, S.-H.; Wiik, P.; Ueno, Y.; Matsuda, A.; Seeberg, E. (1998). Addition of 5-formyldeoxyuridine to the growth medium of bacteria and mammalian cells causes mutations.
  • Bjelland, Svein; Klungland, A.; Ueno, Y.; Matsuda, A.; Seeberg, E. (1998). 5-Formyldeoxyuridine-induced mutagenesis in bacteria and mammalian cells.
  • Bjelland, Svein; Klungland, A.; Ånensen, H.; Provan, Fiona; Selmer, S.-H.; Lian, A.T.; Wiik, P.; Ueno, Y.; Matsuda, A.; Seeberg, E. (1998). 5-formyldeoxyuridine-induced mutagenesis in bacteria and mammalian cells.
  • Bjelland, Svein (1996). Mutagenicity of an oxidized thymine base and its nucleoside-5 -formyluracil and 5-formyldeoxyuridine- to mammalian cells. 1996-01-21.