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This is the study programme for 2019/2020. It is subject to change.


The course gives an introduction to molecular genetics, gene regulation, cell cycle regulation, basic methods in gene technology and bioinformatics.

Learning outcome

  • Understand how genes are assembled and the mechanisms for gene expression.
  • Know the principles of central gene technological methods and methods to map genomes, genetic variation and gene expression.
  • Understand the mechanisms for gene regulation both in prokaryotes and in eukaryotes.
  • Know the regulation of the cell cycle in relation to the development of cancer.
  • Have basic knowledge about bioinformatics.
  • Use web-based bioinformatics tools to solve problems

Contents

The course starts with the principles of classical genetics in view of our present understanding about cell division and the organization of chromosomes. The structure and organization of genes and mechanisms for gene expression will be covered. The most central methods in molecular genetics will be introduced, followed by lessons about gene regulation, genetic variation and cell cycle control. Modern methods for large scale studies of genomes and gene expression will be presented. Furthermore, defined defects in a cell's control mechanisms will be used to illustrate how these defects can lead to disease, as for example cancer. Finally, basic methods in bioinformatics will be introduced and used to solve problems.

Required prerequisite knowledge

None.

Recommended previous knowledge

BIO100 Cell Biology, BIO200 Biochemistry, BIO210 Biotechnology, KJE200 Organic Chemistry 1

Exam

Weight Duration Marks Aid
Written exam1/14 hoursA - FNone permitted

Coursework requirements

Two assignments
Two compulsory assignments must be completed in order to attend course examination.

Course teacher(s)

Course teacher
Oddmund Nordgård
Course coordinator
Oddmund Nordgård , Heinz Peter Ruoff
Head of Department
Gro Johnsen

Method of work

Four hours lectures per week. Solving excercises with computer assistance.

Overlapping courses

Course Reduction (SP)
Gene technology (MOT190_1) 5
Introduction to Bioinformatics (BBI100_1) 5

Open to

Bachelor level studies at the Faculty of Science and Technology

Master level studies at the Faculty of Science and Technology

Course assessment

Forms and/or discussion.

Literature

1) Genetics: From Genes to Genomes (Hartwell et al.), McGrawHill, latest edition. Chapters will be announced at the start of the course.
2) Bioinformatics and Functional Genomics (Pevsner), Wiley-Blackwell, latest edition. Chapters will be announced at the start of the course.


This is the study programme for 2019/2020. It is subject to change.

Sist oppdatert: 22.08.2019