After an introduction to spectrometric analytical techniques, the student will learn to combine the structural information from NMR/UV/IR/MS-spectra to confirm or reveal the structure of small to medium sized organic molecules.
Course description for study year 2022-2023. Please note that changes may occur.
A discussion of the principles for common spectrometry-techniques like MS, IR, NMR (H, C,DEPT, HSQC,COSY, ROSY, HMBC) and UV; will be followed by a systematic examination of the techniques and the structural information they give for organic molecules. An important part of this subject is to be able to utilize acquired spectrometry-knowledge to obtain structural information from spectra and combine this information to deduce an unambiguous structure of organic molecules. The department's spectrometry-equipment will be applied for some practical work on unknown samples.
A candidate with a completed course will know spectrometry techniques like UV, IR, NMR and MS, and know what structural information can be obtained from different spectra, incuding DEPT and 2D-techniques like COSY, ROSY, HSQC and HMBC. The candidate should be able to combine this information and deduce the structure of organic molecules from their spectra, and control that the structure comply with all data. The candidate will be able to suggest supplementary experiments to obtain required information to obtain an unambiguous structure of an unknown molecule. The candidate will be able to obtain spectra from the department's spectrometry-equipment (UV/IR/NMR/MS).
Required prerequisite knowledge
KJE200 Organic Chemistry 1
MLJ540 Instrumental Analysis
Form of assessment
Approved, basic calculator, One A4 sheet of handwritten notes., Textbook containing notes.,
Mandatory laboratory work
Mandatory laboratory work (3-5 days) must be completed.