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Emiel Janssen

professor in biomedicine

Stavanger
Det teknisk- naturvitenskapelige fakultet

Institutt for kjemi, biovitenskap og miljøteknologi
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Bio

Based on my experience, I have come to appreciate the major problem of over- and undertreatment of  cancer patients and its impacts on patients and healthcare systems. My research program is devoted to diminishing patient suffering from over- and undertreatment by developing better diagnostics for treatment decision making. The development, validation and implementation of new biomarkers is the main focus of our research. My laboratory has particular expertise in RNA profiling, including analysis of gene expression and microRNAs. Furthermore we use digital pathology, image analysis tools, and artificial intelligence algorithms to improve current diagnostics in pathology. Breast cancer, gynecological cancer and urological cancer are the main malignancies that we investigate.

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Publications
  • Vitenskapelige publikasjoner
    • Ben-Elazar, Shay; Aure, Miriam Ragle; Jonsdottir, Kristin; Leivonen, Suvi-Katri; Kristensen, Vessela N.; Janssen, Emiel; Sahlberg, Kristine Kleivi; Lingjærde, Ole Christian; Yakhini, Zohar

      (2021)

      miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer.

      PLoS Computational Biology

      ISSN 1553-734X.

      Volum 17.

      Hefte 2.

      DOI: 10.1371/JOURNAL.PCBI.1008608

    • Wetteland, Rune; Engan, Kjersti; Eftestøl, Trygve Christian; Kvikstad, Vebjørn; Janssen, Emiel

      (2020)

      A Multiscale Approach for Whole-Slide Image Segmentation of five Tissue Classes in Urothelial Carcinoma Slides.

      Technology in Cancer Research and Treatment

      ISSN 1533-0346.

      Volum 19.

      s.1-15.

      DOI: 10.1177/1533033820946787

    • Dalheim, Ove Nicolai; Wetteland, Rune; Kvikstad, Vebjørn; Janssen, Emiel; Engan, Kjersti

      (2020)

      Semi-supervised tissue segmentation of histological images.

      CEUR Workshop Proceedings

      ISSN 1613-0073.

      Volum 2688.

    • Viste, Eirik; Vinje, Cathrine Alvær; Lid, Torgeir Gilje; Skeie, Svein; Olsen, Øystein Evjen; Nordström, Tobias; Thorsen, Olav; Gilje, Bjørnar; Janssen, Emiel; Kjosavik, Svein Reidar

      (2020)

      Effects of replacing PSA with Stockholm3 for diagnosis of clinically significant prostate cancer in a healthcare system – the Stavanger experience.

      Scandinavian Journal of Primary Health Care

      ISSN 0281-3432.

      Volum 38.

      Hefte 3.

      s.315-322.

      DOI: 10.1080/02813432.2020.1802139

    • Egeland, Nina Gran; Jonsdottir, Kristin; Aure, Miriam Ragle; Sahlberg, Kristine Kleivi; Kristensen, Vessela N.; Cronin-Fenton, Deirdre; Skaland, Ivar; Gudlaugsson, Einar; Baak, Jan P.A.; Janssen, Emiel

      (2020)

      MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers.

      BMC Cancer

      ISSN 1471-2407.

      Volum 20.

      DOI: 10.1186/s12885-020-06857-7

    • Lillesand, Melinda; Kvikstad, Vebjørn; Mangrud, Målfrid Ok; Gudlaugsson, Einar; Van Diermen, Bianca; Skaland, Ivar; Baak, Johannes Peter A; Janssen, Emiel

      (2020)

      Mitotic activity index and CD25+ lymphocytes predict risk of stage progression in non-muscle invasive bladder cancer.

      PLOS ONE

      ISSN 1932-6203.

      Volum 15.

      Hefte 6.

      DOI: 10.1371/journal.pone.0233676

    • Egeland, Nina Gran; Jonsdottir, Kristin; Lauridsen, Kristina Lystlund; Skaland, Ivar; Hjorth, Cathrine F.; Gudlaugsson, Einar; Hamilton-Dutoit, Stephen Jacques; Lash, Timothy L.; Cronin-Fenton, Deidre; Janssen, Emiel

      (2020)

      Digital Image Analysis of Ki-67 Stained Tissue Microarrays and Recurrence in Tamoxifen-Treated Breast Cancer Patients.

      Clinical Epidemiology

      ISSN 1179-1349.

      Volum 12.

      s.771-781.

      DOI: 10.2147/CLEP.S248167

    • Ogden, Angela; Bhattarai, Shristi; Sahoo, Bikram; Mongan, Nigel P.; Alsaleem, Mansour; Green, Andrew R.; Aleskandarany, Mohammed ; Ellis, Ian O.; Pattni, Sonal; Li, Xiaoxian Bill; Moreno, Carlos S.; Krishnamurti, Uma; Janssen, Emiel; Jonsdottir, Kristin; Rakha, Emad; Rida, Padmashree; Aneja, Ritu

      (2020)

      Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers.

      Scientific Reports

      ISSN 2045-2322.

      Volum 10.

      DOI: 10.1038/s41598-020-59514-1

    • Eikesdal, Hans Petter; Yndestad, Synnøve; Elzawahry, Asmaa; Llop-Guevara, Alba; Gilje, Bjørnar; Blix, Egil Støre; Espelid, Helge; Lundgren, Steinar; Geisler, Jürgen; Vagstad, Geirfinn; Venizelos, Andreas; Minsaas, Laura; Leirvaag, Beryl; Gudlaugsson, Einar; Vintermyr, Olav Karsten; Aase, Hildegunn Siv; Aas, Turid; Balmaña, Judith; Serra, Violeta; Janssen, Emiel; Knappskog, Stian; Lønning, Per Eystein

      (2020)

      Olaparib monotherapy as primary treatment in unselected triple negative breast cancer.

      Annals of Oncology

      ISSN 0923-7534.

      s.1-10.

      DOI: 10.1016/j.annonc.2020.11.009

    • Ghimire, Hemendra; Garlapati, Chakravarthy; Janssen, Emiel; Krishnamurti, Uma; Qin, Gengsheng; Aneja, Ritu; Unil Perera, Perera

      (2020)

      Protein conformational changes in breast cancer sera using infrared spectroscopic analysis.

      Cancers

      ISSN 2072-6694.

      Volum 12.

      Hefte 7.

      DOI: 10.3390/cancers12071708

    • Helland, Thomas; Naume, Bjørn; Hustad, Steinar; Bifulco, Ersilia; Kvaløy, Jan Terje; Sætersdal, Anna Barbro; Synnestvedt, Marit; Lende, Tone Hoel; Gilje, Bjørnar; Mjaaland, Ingvil; Weyde, Kjetil; Blix, Egil Støre; Wiedswang, Gro; Borgen, Elin; Hertz, Daniel Louis; Janssen, Emiel; Mellgren, Gunnar; Søiland, Håvard

      (2020)

      Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen.

      Molecular Oncology

      ISSN 1574-7891.

      DOI: 10.1002/1878-0261.12865

    • Mittal, Karuna; Kaur, Jaspreet; Jaczko, Meghan; Wei, Guanhao; Toss, Michael S.; Rakha, Emad A.; Janssen, Emiel; Søiland, Håvard; Kucuk, Omer; Reid, Michelle D; Gupta, Meenakshi V; Aneja, Ritu

      (2020)

      Centrosome amplification: a quantifiable cancer cell trait with prognostic value in solid malignancies.

      Cancer Metastasis Review

      ISSN 0167-7659.

      Volum 40.

      s.319-339.

      DOI: 10.1007/s10555-020-09937-z

    • Bicskei, Beatrix; Moltu, Pia; Lillesand, Melinda; Rewcastle, Emma; Christiansen, Irene Kraus; Gudlaugsson, Einar; Berland, Jannicke; Janssen, Emiel; Øvestad, Irene Tveiterås

      (2020)

      A comparison of the Linear Array and the Automated INNO-LiPA HPV Genotyping Systems on Pathological Specimens.

      Journal of Cancer Science and Clinical Therapeutics

      ISSN 2637-5079.

      Volum 4.

      Hefte 3.

      s.349-364.

      DOI: 10.26502/jcsct.5079077

    • Petcu, Eugen B.; Andry, Christopher; Burks, Eric J.; Hamlet, Stephen; Janssen, Emiel; Kjellevold, Kjell H; de Las Morenas, Antonio; Miller, Nancy S.; Miroiu, Rodica I.; Nusem, Iulian; Popa-Wagner, Aurel

      (2020)

      The SARS-CoV2 - ACE2 link: a physiopathological analysis.

      Vascular Cell

      Volum 12.

      Hefte 1.

      DOI: 10.24238/13221-12-1-197

    • Mittal, Karuna; Toss, Michael S.; Wei, Guanhao; Kaur, Jaspreet; Choi, Da Hoon; Melton, Brian D.; Osan, Remus M.; Miligy, Islam M.; Green, Andrew R.; Janssen, Emiel; Søiland, Håvard; Gogineni, Keerthi; Manne, Upender; Rida, Padmashree; Rakha, Emad A.; Aneja, Ritu

      (2020)

      A Quantitative Centrosomal Amplification Score Predicts Local Recurrence of Ductal Carcinoma In Situ.

      Clinical Cancer Research

      ISSN 1078-0432.

      Volum 26.

      Hefte 12.

      s.2898-2907.

      DOI: 10.1158/1078-0432.CCR-19-1272

    • Kvikstad, Vebjørn; Mangrud, Målfrid Ok; Gudlaugsson, Einar; Dalen, Ingvild; Espeland, Hans; Baak, Jan P.A.; Janssen, Emiel

      (2019)

      Prognostic value and reproducibility of different microscopic characteristics in the WHO grading systems for pTa and pT1 urinary bladder urothelial carcinomas.

      Diagnostic Pathology

      ISSN 1746-1596.

      Volum 14.

      DOI: 10.1186/s13000-019-0868-3

    • Egeland, Nina Gran; Austdal, Marie; Van Diermen, Bianca; Rewcastle, Emma; Gudlaugsson, Einar; Baak, Jan P.A.; Skaland, Ivar; Janssen, Emiel; Jonsdottir, Kristin

      (2019)

      Validation study of MARCKSL1 as a prognostic factor in lymph node-negative breast cancer patients.

      PLOS ONE

      ISSN 1932-6203.

      Volum 14:e0212527.

      Hefte 3.

      s.1-12.

      DOI: 10.1371/journal.pone.0212527

    • Lende, Tone Hoel; Austdal, Marie; Varhaugvik, Anne Elin; Skaland, Ivar; Gudlaugsson, Einar; Kvaløy, Jan Terje; Akslen, Lars A.; Søiland, Håvard; Janssen, Emiel; Baak, Jan P.A.

      (2019)

      Influence of pre-operative oral carbohydrate loading vs. standard fasting on tumor proliferation and clinical outcome in breast cancer patients - a randomized trial.

      BMC Cancer

      ISSN 1471-2407.

      Volum 19:1076.

      s.1-22.

      DOI: 10.1186/s12885-019-6275-z

    • Bhattarai, Shristi; Klimov, Sergey; Mittal, Karuna; Krishnamurti, Uma; Li, Xiaoxian Bill; Oprea-Ilies, Gabriela; Wetherilt, Ceyda Sonmez; Riaz, Ansa; Aleskandarany, Mohammed A.; Green, Andrew R.; Ellis, Ian O; Cantuaria, Guilherme; Gupta, Meenakshi; Manne, Upender; Agboola, Johnson; Baskovich, Brett; Janssen, Emiel; Callagy, Grace; Walsh, Elaine M.; Mehta, Anurag; Dogra, Atika; Shet, Tanuja; Gajaria, Pooja; Traina, Tiffany; Nggada, Haruna A.; Omonisi, Abidemi; Ahmed, Saad A.; Rakha, Emad A.; Rida, Padmashree; Aneja, Ritu

      (2019)

      Prognostic role of androgen receptor in triple negative breast cancer: A multi-institutional study.

      Cancers

      ISSN 2072-6694.

      Volum 11:995.

      Hefte 7.

      s.1-9.

      DOI: 10.3390/cancers11070995

    • Oskal, Kay Raymond; Risdal, Martin; Janssen, Emiel; Undersrud, Erling Sandøy; Gulsrud, Thor Ole

      (2019)

      A U‑net based approach to epidermal tissue segmentation in whole slide histopathological images.

      SN Applied Sciences

      ISSN 2523-3963.

      Volum 1.

      DOI: 10.1007/s42452-019-0694-y

    • Wetteland, Rune; Engan, Kjersti; Eftestøl, Trygve Christian; Kvikstad, Vebjørn; Janssen, Emiel

      (2019)

      Multiclass tissue classification of whole-slide histological images using convolutional neural networks. I: Proceedings of the 8th International Conference on Pattern Recognition Applications and Methods.

      SciTePress

      ISBN 978-989-758-351-3.

      s.320-327.

      DOI: 10.5220/0007253603200327

    • Lende, Tone Hoel; Austdal, Marie; Bathen, Tone Frost; Varhaugvik, Anne Elin; Skaland, Ivar; Gudlaugsson, Einar; Egeland, Nina Gran; Lunde, Siri; Akslen, Lars A.; Jonsdottir, Kristin; Janssen, Emiel A.M.; Søiland, Håvard; Baak, Jan P.A.

      (2019)

      Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study.

      BMC Cancer

      ISSN 1471-2407.

      Volum 19:1183.

      s.1-23.

      DOI: 10.1186/s12885-019-6393-7

    • Tjensvoll, Kjersti; Nordgård, Oddmund; Skjæveland, Maren; Oltedal, Satu; Janssen, Emiel; Gilje, Bjørnar

      (2019)

      Detection of disseminated tumor cells in bone marrow predict late recurrences in operable breast cancer patients.

      BMC Cancer

      ISSN 1471-2407.

      Volum 19.

      Hefte 1.

      s.1-11.

      DOI: 10.1186/s12885-019-6268-y

    • Helland, Thomas; Hagen, Kari Britt; Haugstøyl, Martha Eimstad; Kvaløy, Jan Terje; Lunde, Siri; Lode, Kirsten; Lind, Ragna Anne; Gripsrud, Birgitta Haga; Jonsdottir, Kristin; Gjerde, Jennifer; Bifulco, Ersilia; Hustad, Simon Steinar; Jonassen, Janne; Aas, Turid; Lende, Tone Hoel; Lien, Ernst Asbjørn; Janssen, Emiel; Søiland, Håvard; Mellgren, Gunnar

      (2019)

      Drug monitoring of tamoxifen metabolites predicts vaginal dryness and verifies a low discontinuation rate from the Norwegian Prescription Database.

      Breast Cancer Research and Treatment

      ISSN 0167-6806.

      Volum 177.

      Hefte 1.

      s.185-195.

      DOI: 10.1007/s10549-019-05294-w

    • Saini, Geetanjali; Mittal, Karuna; Rida, Padmashree; Janssen, Emiel; Gogineni, Keerthi; Aneja, Ritu

      (2019)

      Panoptic view of prognostic models for personalized breast cancer management.

      Cancers

      ISSN 2072-6694.

      Volum 11:1325.

      Hefte 9.

      s.1-23.

      DOI: 10.3390/cancers11091325

    • Bozickovic, Olivera; Skartveit, Linn; Svendsen, Agnete; Helland, Thomas; Jonsdottir, Kristin; Flågeng, Marianne Hauglid; Fenne, Ingvild Sveinsgjerd; Janssen, Emiel; Lorens, James; Bjørkhaug, Lise; Sagen, Jørn V.; Mellgren, Gunnar

      (2018)

      A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells.

      Journal of Steroid Biochemistry and Molecular Biology

      ISSN 0960-0760.

      Volum 185.

      s.57-70.

      DOI: 10.1016/j.jsbmb.2018.07.011

    • Oltedal, Satu; Skaland, Ivar; Maple-Grødem, Jodi; Tjensvoll, Kjersti; Janssen, Emiel; Gilje, Bjørnar; Smaaland, Rune; Heikkilä, Reino; Nordgård, Oddmund

      (2018)

      Expression profiling and intracellular localization studies of the novel Proline-, Histidine-, and Glycine-rich protein 1 suggest an essential role in gastro-intestinal epithelium and a potential clinical application in colorectal cancer diagnostics.

      BMC Gastroenterology

      ISSN 1471-230X.

      Volum 18.

      Hefte 26.

      DOI: 10.1186/s12876-018-0752-8

    • Koeneman, Margot M.; Øvestad, Irene Tveiterås; Janssen, Emiel; Ummelen, Monique; Kruitwagen, Roy F.P.M.; Hopman, Anton H.; Kruse, Arnold J.

      (2018)

      Gain of chromosomal region 3q26 as a prognostic biomarker for high-grade cervical intraepithelial neoplasia: Literature overview and pilot study.

      Pathology and Oncology Research

      ISSN 1219-4956.

      s.1-9.

      DOI: 10.1007/s12253-018-0480-y

    • Rewcastle, Emma; Varhaugvik, Anne Elin; Gudlaugsson, Einar; Steinbakk, Anita; Skaland, Ivar; Van Diermen, Bianca; Baak, Jan P.A.; Janssen, Emiel

      (2018)

      Assessing the prognostic value of PAX2 and PTEN in endometrial carcinogenesis.

      Endocrine-Related Cancer

      ISSN 1351-0088.

      Volum 25.

      Hefte 12.

      s.981-991.

      DOI: 10.1530/ERC-18-0106

    • Klimov, Sergey; Rida, Padmashree CG; Aleskandarany, Muhammed A.; Green, Andrew R.; Ellis, Ian O.; Janssen, Emiel; Rakha, Emad A.; Aneja, Ritu

      (2017)

      Novel immunohistochemistry-based signatures to predict metastatic site of triple-negative breast cancers.

      British Journal of Cancer

      ISSN 0007-0920.

      Volum 117.

      Hefte 6.

      s.826-834.

      DOI: 10.1038/bjc.2017.224

    • Klebaner, Daniella; Hamilton-Dutoit, Stephen; Ahern, Thomas; Crawford, Anatasha; Jakobsen, Thomas; Cronin-Fenton, Deirdre P.; Damkier, Per; Janssen, Emiel; Kjærsgaard, Anders; Ording, Anne Gulbech; Søiland, Håvard; Sørensen, Henrik Toft; Lash, Timothy L.; Hellberg, Ylva

      (2017)

      Apolipoprotein D expression does not predict breast cancer recurrence among tamoxifentreated patients.

      PLOS ONE

      ISSN 1932-6203.

      Volum 12:e0171453.

      Hefte 3.

      s.1-12.

      DOI: 10.1371/journal.pone.0171453

    • Helland, Thomas; Henne, Nina; Bifulco, Ersilia; Naume, Bjørn; Borgen, Elin; Kristensen, Vessela N.; Kvaløy, Jan Terje; Lash, Timothy L; Grenaker, Grethe Irene; van Schaik, RHN; Janssen, Emiel; Hustad, Simon Steinar; Lien, Ernst Asbjørn; Mellgren, Gunnar; Søiland, Håvard

      (2017)

      Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients.

      Breast Cancer Research

      ISSN 1465-5411.

      Volum 19.

      Hefte 1.

      DOI: 10.1186/s13058-017-0916-4

    • Urdal, Jarle; Engan, Kjersti; Kvikstad, Vebjørn; Janssen, Emilius

      (2017)

      Prognostic Prediction of Histopathological Images by Local Binary Patterns and RUSBoost.

      European Signal Processing Conference

      ISSN 2076-1465.

      s.2349-2353.

      DOI: 10.23919/EUSIPCO.2017.8081630

    • Damkier, Per; Kjærsgaard, Anders; Barker, Kimberly; Cronin-Fenton, Deidre; Crawford, Anatasha; Hellberg, Ylva; Janssen, Emiel; Langefeld, Carl; Ahern, Thomas P.; Lash, Timothy L.

      (2017)

      CYP2C19*2 and CYP2C19*17 variants and effect of tamoxifen on breast cancer recurrence: Analysis of the International Tamoxifen Pharmacogenomics Consortium dataset.

      Scientific Reports

      ISSN 2045-2322.

      Volum 7.

      Hefte 1.

      DOI: 10.1038/s41598-017-08091-x

    • Mittal, Karuna; Choi, Da Hoon; Ogden, Angela; Donthamsetty, Shashi; Melton, Brian D; Gupta, Meenakshi V; Pannu, Vaishali; Cantuaria, Guilherme; Varambally, Sooryanarayana; Reid, Michelle D; Jonsdottir, Kristin; Janssen, Emiel; Aleskandarany, Muhammed A.; Ellis, Ian O.; Rakha, Emad A.; Rida, Padmashree CG; Aneja, Ritu

      (2017)

      Amplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cells.

      Scientific Reports

      ISSN 2045-2322.

      Volum 7.

      DOI: 10.1038/srep43984

    • Norheim, Katrine Brække; Imgenberg-Kreuz, Juliana; Jonsdottir, Kristin; Janssen, Emiel; Syvänen, Ann-Christine; Sandling, Johanna K.; Nordmark, Gunnel; Omdal, Roald

      (2016)

      Epigenome-wide DNA methylation patterns associated with fatigue in primary Sjögren's syndrome.

      Rheumatology

      ISSN 1462-0324.

      Volum 55.

      Hefte 6.

      s.1074-1082.

      DOI: 10.1093/rheumatology/kew008

    • Engesæter, Birgit Øvstebø; Van Diermen, Bianca; Hansen, Mona Lindsethmo; Moltu, Pia; Mangseth, Kjersti; Borchgrevink-Persen, Siri; Vintermyr, Olav Karsten; Lönnberg, Stefan; Nygård, Mari; Janssen, Emiel; Castle, Philip E.; Kraus, Hanne Irene

      (2016)

      Quality assurance of human papillomavirus (HPV) testing in the implementation of HPV primary screening in Norway: An inter-laboratory reproducibility study.

      BMC Infectious Diseases

      ISSN 1471-2334.

      Volum 16.

      DOI: 10.1186/s12879-016-2028-7

    • Johnsen, Svein Joar Auglæn; Gudlaugsson, Einar; Skaland, Ivar; Janssen, Emiel; Jonsson, Malin V; Helgeland, Lars; Berget, Ellen; Jonsson, Roland; Omdal, Roald

      (2016)

      Low protein A20 in minor salivary glands is associated with lymphoma development in primary Sjögren's syndrome.

      Scandinavian Journal of Immunology

      ISSN 0300-9475.

      Volum 83.

      Hefte 3.

      s.181-187.

      DOI: 10.1111/sji.12405

    • Førsvoll, Jostein Andersen; Janssen, Emilius Adrianus Maria; Møller, Ingegerd; Wathne, Nina; Skaland, Ivar; Klos, Jan; Kristoffersen, Einar Klæboe; Øymar, Knut

      (2015)

      Reduced number of CD8+ cells in tonsillar germinal centres in children with the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome.

      Scandinavian Journal of Immunology

      ISSN 0300-9475.

      Volum 82.

      Hefte 1.

      s.76-83.

      DOI: 10.1111/sji.12303

    • Egeland, Nina Gran; Lunde, Siri; Jonsdottir, Kristin; Lende, Tone Hoel; Cronin-Fenton, Deirdre P.; Gilje, Bjørnar; Janssen, Emilius Adrianus Maria; Søiland, Håvard

      (2015)

      The role of microRNAs as predictors of response to tamoxifen treatment in breast cancer patients.

      International Journal of Molecular Sciences

      ISSN 1422-0067.

      Volum 16.

      Hefte 10.

      s.24243-24275.

      DOI: 10.3390/ijms161024243

    • Mangrud, Målfrid Ok; Waalen, Rune; Gudlaugsson, Einar; Dalen, Ingvild; Tasdemir, Ilker; Janssen, Emilius Adrianus Maria; Baak, Jan P.A.

      (2014)

      Reproducibility and prognostic value of WHO1973 and WHO2004 grading systems in TaT1 urothelial carcinoma of the urinary bladder.

      PLOS ONE

      ISSN 1932-6203.

      Volum 9.

      Hefte 1:e83192.

      DOI: 10.1371/journal.pone.0083192

    • Mangrud, Målfrid Ok; Gudlaugsson, Einar; Skaland, Ivar; Tasdemir, Ilker; Dalen, Ingvild; Van Diermen, Bianca; Baak, Jan P.A.; Janssen, Emilius Adrianus Maria

      (2014)

      Prognostic comparison of proliferation markers and World Health Organization 1973/2004 grades in urothelial carcinomas of the urinary bladder.

      Human Pathology

      ISSN 0046-8177.

      Volum 45.

      Hefte 7.

      s.1496-1503.

      DOI: 10.1016/j.humpath.2014.03.001

    • Jonsdottir, Kristin; Assmus, Jörg; Slewa, Aida; Gudlaugsson, Einar; Skaland, Ivar; Baak, Jan P.A.; Janssen, Emilius Adrianus Maria

      (2014)

      Prognostic value of gene signatures and proliferation in lymph-node-negative breast cancer.

      PLOS ONE

      ISSN 1932-6203.

      Volum 9.

      Hefte 3:90642.

      DOI: 10.1371/journal.pone.0090642

    • Gudlaugsson, Einar; Klos, Jan; Skaland, Ivar; Janssen, Emilius Adrianus Maria; Smaaland, Rune; Feng, Weiwei; Shao, Zhimin; Malpica, Anais; Baak, Jan P.A.

      (2013)

      PROGNOSTIC COMPARISON OF THE PROLIFERATION MARKERS (MITOTIC ACTIVITY INDEX, PHOSPHOHISTONE H3, KI67), STEROID RECEPTORS, HER2, HIGH MOLECULAR WEIGHT CYTOKERATINS AND CLASSICAL PROGNOSTIC FACTORS IN T1-2N0M0 BREAST CANCER.

      Polish Journal of Pathology

      ISSN 1233-9687.

      Volum 64.

      Hefte 1.

      s.1-8.

      DOI: 10.5114/PJP.2013.34596

    • Feng, Weiwei; Malpica, Anais; Yu, Yinhua; Janssen, Emilius Adrianus Maria; Gudlaugsson, Einar; Zhou, Xianrong; Baak, Jan P.A.

      (2013)

      Diagnostic and prognostic morphometric features in WHO2003 invasive endometrial stromal tumours.

      Histopathology

      ISSN 0309-0167.

      Volum 62.

      Hefte 5.

      s.688-694.

      DOI: 10.1111/j.1365-2559.2011.04120.x

    • Klintman, Marie; Strand, Carina; Ahling, Cecilia; Beglerbegovic, Sanda; Fjällskog, Marie-Louise; Grabau, Dorthe; Gudlaugsson, Einar; Janssen, Emilius Adrianus Maria; Lövgren, Kristina; Skaland, Ivar; Bendahl, Pär-Ola; Malmström, Per; Baak, Jan P.A.; Fernö, Mårten

      (2013)

      The Prognostic Value of Mitotic Activity Index (MAI), Phosphohistone H3 (PPH3), Cyclin B1, Cyclin A, and Ki67, Alone and in Combinations, in Node-Negative Premenopausal Breast Cancer.

      PLOS ONE

      ISSN 1932-6203.

      Volum 8.

      Hefte 12.

      DOI: 10.1371/journal.pone.0081902

    • Øvestad, Irene Tveiterås; Vennestrøm, Undis; Andersen, Liv; Janssen, Emilius Adrianus Maria; Baak, Jan P.A.

      (2012)

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  • Bøker og kapitler
    • Janssen, Emilius Adrianus Maria

      (2007)

      Proliferation and Molecular factors in Lymph Node negative breast cancer.

      Universitetet i Bergen

  • Formidling
    • Wetteland, Rune; Engan, Kjersti; Kvikstad, Vebjørn; Eftestøl, Trygve Christian; Janssen, Emiel

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      Multiscale Deep Neural Networks for Multiclass Tissue Classification of Histological Whole-Slide Images.

      Medical Imaging with Deep Learning: MIDL 2019

    • Eikesdal, Hans Petter; Clausen, Christina; Blix, Egil Støre; Lundgren, Steinar; Vagstad, Geirfinn; Espelid, Helge; Gilje, Bjørnar; Janssen, Emiel; Geisler, Jürgen; Aas, Turid; Aase, Hildegunn Siv; Knappskog, Stian; Lønning, Per Eystein

      (2019)

      Neoadjuvant endocrine therapy with palbociclib in patients with high-risk breast cancer.

    • Eikesdal, Hans Petter; Yndestad, Synnøve; Blix, Egil Støre; Lundgren, Steinar; Vagstad, Geirfinn; Espelid, Helge; Gilje, Bjørnar; Janssen, Emiel; Geisler, Jürgen; Aas, Turid; Aase, Hildegunn Siv; Knappskog, Stian; Lønning, Per Eystein

      (2019)

      Neoadjuvant olaparib monotherapy in primary triple negative breast cancer.

    • Wetteland, Rune; Engan, Kjersti; Eftestøl, Trygve Christian; Kvikstad, Vebjørn; Janssen, Emiel

      (2018)

      Histological Image Segmentation of Bladder Cancer Using Machine Learning.

    • Lunde, Siri; Helland, Thomas; Jonassen, Janne; Martha, Haugstøyl; Austdal, Marie; Lode, Kirsten; Hagen, Kari-Britt; Gripsrud, Birgitta Haga; Lind, Ragna Anne; Gjerde, Jennifer; Lende, Tone Hoel; Gilje, Bjørnar; Aas, Turid; Jonsdottir, Kristin; Kroksveen, Ann Cathrine; Erdal, Bjørg; Vevle, Sissel; Sagen, Jørn-Vegard; Oltedal, Satu; Nordgård, Oddmund; Tjensvoll, Kjersti; Lash, Timothy; Kvaløy, Jan Terje; Janssen, Emiel; Mellgren, Gunnar; Søiland, Håvard; Lien, Ernst Asbjørn

      (2018)

      A prospective, longitudinal, breast cancer biobank (PBCB) in western Norway.

    • Oskal, Kay Raymond; Risdal, Martin; Gulsrud, Thor Ole; Janssen, Emiel

      (2018)

      A Deep Learning Approach to Semantic Segmentation of Epidermal Tissue in Whole Slide Histopathological Images.

    • Risdal, Martin; Gulsrud, Thor Ole; Janssen, Emiel

      (2018)

      Virtual staining simulator for computational pathology method development.

    • Urdal, Jarle; Engan, Kjersti; Kvikstad, Vebjørn; Janssen, Emiel

      (2017)

      Prognostic Prediction of Histopathological Images by Local Binary Patterns and RUSBoost.

    • Engesæter, Birgit Øvstebø; Van Diermen, Bianca; Hansen, Mona; Moltu, Pia; Borchgrevink-Persen, Siri; Vintermyr, Olav Karsten; Lönnberg, Stefan; Nygård, Mari; Janssen, Emiel

      (2016)

      Inter-laboratory reproducibility of the cobas 4800 HPV test in cervical cancer screening in Norway.

    • Mangrud, OM; Hidle, BD; Waalen, R; Gudlaugsson, Einar; Janssen, Emilius Adrianus Maria; Baak, Jan P.A.

      (2011)

      A Comparison of Proliferation Markers in Urothelial Carcinomas of the Urinary Bladder.

      Modern Pathology

      ISSN 0893-3952.

      Volum 24.

      s.209A-209A.

    • Mangrud, OM; Hidle, BD; Waalen, R; Gudlaugsson, Einar; Janssen, Emilius Adrianus Maria; Baak, Jan P.A.

      (2011)

      A Comparison of Proliferation Markers in Urothelial Carcinomas of the Urinary Bladder.

      Laboratory Investigation

      ISSN 0023-6837.

      Volum 91.

      s.209A-209A.

    • Øvestad, Irene Tveiterås; Janssen, Emilius Adrianus Maria; Kjellevold, Kjell H; Baak, Jan P.A.

      (2010)

      HPV-testing ved Stavanger universitetssjukehus.

      Tidsskrift for Den norske legeforening

      ISSN 0029-2001.

      Volum 130.

      Hefte 22.

    • Gudlaugsson, Einar; Skaaland, I.; Janssen, Emilius Adrianus Maria; Søiland, Håvard; Malpica, A.; Baak, Jan P.A.

      (2010)

      Comparing the prognostic value of proliferation markers Ki67, mitotic activity index, phosphohistone-3 and classical variables in breast cancer.

      Virchows Archiv

      ISSN 0945-6317.

      Volum 457.

      Hefte 2.

      s.170-170.

    • Gudlaugsson, Einar; Skaland, Ivar; Janssen, Emilius Adrianus Maria; Smaaland, Rune; Søiland, Håvard; Baak, Jan P.A.

      (2010)

      In operable node negative breast cancer patients under 71 years, lymph vessel invasion has no additional prognostic value to PhosphoHistone-3 proliferative activity.

      APMIS - Journal of Pathologiy, Microbiology and Immunology

      ISSN 0903-4641.

      Volum 118.

      Hefte 3.

      s.250-250.

    • Gudlaugsson, Einar; van Diest, Paul J; Voorhorst, Feja J.; Zhiming, Shao; Kjellevold, Kjell H; zur Hausen, A; Janssen, Emilius Adrianus Maria; Baak, Jan P.A.

      (2010)

      Validation of the prospective multicenter predictive value of proliferation in lymph node positive breast cancer.

      APMIS - Journal of Pathologiy, Microbiology and Immunology

      ISSN 0903-4641.

      Volum 118.

      Hefte 3.

      s.251-252.

    • Lende, Tone Hoel; Gudlaugsson, Einar; Janssen, Emilius Adrianus Maria; Voorhorst, F; van Diest, PJ; Søiland, Håvard; Baak, Jan P.A.

      (2009)

      Mitotic Activity Index Identifies Both Over- and Undertreated Lymph Node Negative Breast Cancer Patients < 55 Year According to the Norwegian Treatment Guidelines.

      Cancer Research

      ISSN 0008-5472.

      Volum 69.

      Hefte 24.

      s.706S-706S.

    • Palmer, Julia E.; Cassia, Louis J. Sant; Irwin, Clive J.; Morris, Alan G.; Janssen, Emilius Adrianus Maria; Baak, Jan P.A.; Rollason, Terence P.

      (2008)

      Manual and computer-aided image analysis measurements of angiogenesis and their ability to predict chemotherapy response in serous carcinoma of the ovary.

      BJOG: An International Journal of Obstetrics and Gynaecology

      ISSN 1470-0328.

      Volum 115.

      Hefte 1.

      s.125-126.

    • Søiland, Håvard; Skaland, Ivar; Van Diermen, Bianca; Janssen, Emilius Adrianus Maria; Kørner, Hartwig; Varhaug, Jan Erik; Søreide, Jon Arne; Baak, Jan P.A.

      (2007)

      Androgen receptor determination in breast cancer: a comparison of the dextran-coated charcoal method and quantitative immunohistochemical analysis.

      Breast Cancer Research and Treatment

      ISSN 0167-6806.

      Volum 106.

      Hefte Suppl 1.

      s.S216-S216.

    • Baak, Jan P.A.; Janssen, Emilius Adrianus Maria; Skaland, Ivar; Gudlaugsson, Einar

      (2007)

      Proliferation is the strongest prognosticator in node-negative breast cancer: error sources and alternatives.

      APMIS - Journal of Pathologiy, Microbiology and Immunology

      ISSN 0903-4641.

      Volum 115.

      Hefte 11.

      s.1315-1316.

    • Skaland, Ivar; Øvestad, Irene T.; Janssen, Emilius Adrianus Maria; Klos, Jan; Kjellevold, Kjell-Henning; Helliesen, Tove; Baak, Jan P.A.

      (2007)

      Comparing subjective and digital image analysis HER2/neu expression scores with conventional and modified FISH scores in breast cancer.

      APMIS - Journal of Pathologiy, Microbiology and Immunology

      ISSN 0903-4641.

      Volum 115.

      s.1315-1315.

    • Steinbakk, Anita; Skaland, Ivar; Gudlaugsson, Einar; Janssen, Emilius Adrianus Maria; Kjellevold, Kjell-Henning; Klos, Jan; Løvslett, Kjell; Fiane, Bernt; Baak, Jan P.A.

      (2007)

      In pFIGO1-2 endometrioid endometrial cancers curettage material, quantitative analysis of combined biomarkers has stronger prognostic value than classical criteria.

      APMIS - Journal of Pathologiy, Microbiology and Immunology

      ISSN 0903-4641.

      Volum 115.

      Hefte 11.

      s.1314-1315.

    • Janssen, Emilius Adrianus Maria; Øvestad, Irene T.; Skaland, Ivar; Søiland, Håvard; Gudlaugson, Einar; Kjellevold, Kjell-Henning; Nysted, Arne; Søreide, Jon Arne; Baak, Jan P.A.

      (2007)

      ARHI (DIRAS3) and proliferation in lymph node negative breast cancer.

      APMIS - Journal of Pathologiy, Microbiology and Immunology

      ISSN 0903-4641.

      Volum 115.

      Hefte 11.

      s.1318-1318.

    • Skaland, Ivar; van Diest, Paul J; Janssen, Emilius Adrianus Maria; Gudlaugsson, Einar; Søiland, Håvard; Baak, Jan P.A.

      (2007)

      Prognostic differences of WHO-assessed mitotic activity index (MAI) and mitotic impression by quick scanning in invasive ductal breast cancer patients under 55 years of age.

      Breast Cancer Research and Treatment

      ISSN 0167-6806.

      Volum 106.

      s.S60-S61.

    • Søiland, Håvard; Janssen, Emilius Adrianus Maria; Skaland, Ivar; Gudlaugsson, Einar; Kørner, Hartwig; Varhaug, Jan Erik; Søreide, Jon Arne; Baak, Jan P.A.

      (2007)

      Tissue microarray and whole sections in small sized study populations for ER-alpha, PR, HER-2 and AR in operable breast cancer: correlation and relevance for prognostication.

      APMIS - Journal of Pathologiy, Microbiology and Immunology

      ISSN 0903-4641.

      Volum 115.

      Hefte 6.

      s.1314-1314.

    • Munk, Ane Cecilie; Kruse, Arnold-Jan; Van Diermen, Bianca; Janssen, Emilius Adrianus Maria; Skaland, Ivar; Baak, Jan P.A.

      (2007)

      Prediction of cervical intraepithelial neoplasia grade 3 (CIN-3) regression.

      APMIS - Journal of Pathologiy, Microbiology and Immunology

      ISSN 0903-4641.

      Volum 115.

      Hefte 11.

      s.1312-1312.

    • Baak, Jan P.A.; van Diest, Paul J; Janssen, Emilius Adrianus Maria; Voorhorst, Feja

      (2007)

      Prospective prognostic value of proliferation in small, low-grade, lymph-node negative breast cancers.

      Breast Cancer Research and Treatment

      ISSN 0167-6806.

      Volum 106.

      s.S64-S64.

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