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Kristian Thorsen

Førsteamanuensis

Det teknisk- naturvitenskapelige fakultet

Institutt for data- og elektroteknologi
KE E-440
Bio

Kristian Thorsen is an Associate Professor in Control Engineering at the University of Stavanger (UiS), Norway. He is currently the leader of the Cybernetics and Systems Biology Laboratories research group.

Teaching and research interests

Cybernetics, dynamic systems, systems biology, synthetic biology, nonlinear systems, control engineering, control theory, mathematical modeling, electronics, embedded systems, signal processing, automation, robotics.

My interest in teaching comes from my own enthusiasm for science and engineering. In my approach to teaching I seek to combine a thorough understanding of theory, facts, and logic reasoning with practical applications and solving of industry relevant problems. I prefer to give courses that bring students into an engineering culture.

My research is focused on using concepts from control engineering to understand regulation in biological systems and on using mathematical models to understand and predict biological phenomena in single cells and in populations of cells and their environment.

ResearchGate profile: https://www.researchgate.net/profile/Kristian_Thorsen
Google Scholar profile: https://scholar.google.no/citations?user=JBSSvZIAAAAJ
Research group page: https://www.uis.no/en/cybernetics-and-systems-biology-laboratories
Full academic CV: Dropbox Link

Teaching experience
ELE340 Embedded design / Computer design (10 ECTS)
Offered in the fifth semester of the bachelor’s degree in electrical engineering. This course gives insight into structured design of embedded systems, i.e., microprocessor-based systems for measurement and control. The students are organized into project groups and project management and a multidiscipline attitude is emphasized. Design exercises in the laboratory forms a main part of the course. Full description: https://www.uis.no/en/course/ELE340_1
Autumn 2016 – 2019, 2020*, 2021 (planned).
ELE600 Advanced control systems and robotics (10 ECTS)
Offered in the second semester of the master’s degree in control engineering. This course deals with feedback control systems, stability analysis, control parameter settings, gain scheduling, cascade control, feed forward control, deadtime compensation and multivariable control. In addition, basic robotic technology, coordinate systems, the Denavit-Hartenberg convention, forward and inverse kinematics, and the use of feedback control for positioning and velocity control of robotic joints. Full description: https://www.uis.no/en/course/ELE600_1
Spring 2017, 2018*, 2019, 2020, 2021*.
YMF100 Introduction to mathematics and physics 1 (10 ECTS)
Offered in the first semester of the bachelor’s degree in electrical engineering (Vocational path / Y-vei). Concepts from pre-calculus and calculus. Numbers, algebra, equations and inequalities. Functions and second order expressions. Logarithms with base 10 and base e. Limits and asymptotes, derivatives, analysis of extrema for functions of one variable. Sequences and series. Physics: primarily movement and force. Full description: https://www.uis.no/en/course/YMF100_1
Autumn 2013.
Introduction to mathematics and physics 2 (YMF110, 10 ECTS)
Offered in the second semester of the bachelor’s degree in electrical engineering (Vocational path / Y-vei). Concepts from calculus. Trigonometric functions. Vectors in 2D and 3D. Integral calculus and methods such as integration by parts and integration by the inverse chain rule. Practical applications of integrals. Probability. Physics: potential and kinetic energy, momentum, and more on force and movement in 2D. Full description: https://www.uis.no/en/course/YMF110_1
Spring 2014 and 2016.

 

*Years where I have been responsible for the course, but the lectures have been given by others.

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Publications
  • Vitenskapelige publikasjoner
    • Thorsen, Kristian; Drengstig, Tormod; Ruoff, Peter

      (2019)

      The effect of integral control in oscillatory and chaotic reaction kinetic networks.

      Physica D : Non-linear phenomena

      ISSN 0167-2789.

      Volum 393.

      s.38-46.

      DOI: 10.1016/j.physd.2019.01.002

    • Ruoff, Peter; Agafonov, Oleg; Tveit, Daniel Myklatun; Thorsen, Kristian; Drengstig, Tormod

      (2019)

      Homeostatic controllers compensating for growth and perturbations.

      PLOS ONE

      ISSN 1932-6203.

      Volum 14.

      Hefte 8.

      DOI: 10.1371/journal.pone.0207831

    • Stokka, Svein Håvard; Jakobsen, Kim Andre; Thorsen, Kristian; Drengstig, Tormod

      (2017)

      Physiological based Modeling and Control of an Industrial Tank Process.

      Linköping Electronic Conference Proceedings

      ISSN 1650-3686.

      s.284-291.

      DOI: 10.3384/ecp17138

    • Risvoll, Geir; Thorsen, Kristian; Ruoff, Peter; Drengstig, Tormod

      (2017)

      Variable setpoint as a relaxing component in physiological control.

      Physiological Reports

      ISSN 2051-817X.

      Volum 5.

      Hefte 17.

      DOI: 10.14814/phy2.13408

    • Tveit, Daniel Myklatun; Thorsen, Kristian

      (2017)

      Passivity-based analysis of biochemical networks displaying homeostasis.

      Linköping Electronic Conference Proceedings

      ISSN 1650-3686.

      s.108-113.

      DOI: 10.3384/ecp17138108

    • Fjeld, Gunhild; Thorsen, Kristian; Drengstig, Tormod; Ruoff, Peter

      (2017)

      Performance of Homeostatic Controller Motifs Dealing with Perturbations of Rapid Growth and Depletion.

      Journal of Physical Chemistry B

      ISSN 1520-6106.

      Volum 121.

      Hefte 25.

      s.6097-6107.

      DOI: 10.1021/acs.jpcb.7b01989

    • Thorsen, Kristian; Risvoll, Geir; Tveit, Daniel Myklatun; Ruoff, Peter; Drengstig, Tormod

      (2016)

      Tuning of Physiological Controller Motifs. I: Proceedings of the 9th EUROSIM Congress on Modelling and Simulation Oulu, Finland 12-16 September 2016.

      IEEE conference proceedings

      ISBN 978-1-5090-4119-0.

      s.28-33.

      DOI: 10.1109/EUROSIM.2016.174

    • Agafonov, Oleg; Selstø, Christina Helen; Thorsen, Kristian; Xu, Xiang Ming; Drengstig, Tormod; Ruoff, Peter

      (2016)

      The organization of controller motifs leading to robust plant iron homeostasis.

      PLOS ONE

      ISSN 1932-6203.

      Volum 11.

      Hefte 1.

      DOI: 10.1371/journal.pone.0147120

    • Thorsen, Kristian; Drengstig, Tormod; Ruoff, Peter

      (2014)

      Transepithelial glucose transport and Na+/K+ homeostasis in enterocytes: an integrative model.

      American Journal of Physiology - Cell Physiology

      ISSN 0363-6143.

      Volum 307.

      Hefte 4.

      s.C320-C337.

      DOI: 10.1152/ajpcell.00068.2013

    • Thorsen, Kristian; Agafonov, Oleg; Selstø, Christina Helen; Jolma, Ingunn Westvik; Ni, Xiaoyu; Drengstig, Tormod; Ruoff, Peter

      (2014)

      Robust Concentration and Frequency Control in Oscillatory Homeostats.

      PLOS ONE

      ISSN 1932-6203.

      Volum 9.

      Hefte 9.

      DOI: 10.1371/journal.pone.0107766

    • Thorsen, Kristian; Ruoff, Peter; Drengstig, Tormod

      (2013)

      Control theoretic properties of physiological controller motifs. I: Proceedings of the IEEE International Conference on System Science and Engineering, ICSSE 2013.

      IEEE conference proceedings

      ISBN 978-1-4799-0007-7.

      s.165-170.

      DOI: 10.1109/icsse.2013.6614653

    • Drengstig, Tormod; Jolma, Ingunn Westvik; Ni, Xiaoyu; Thorsen, Kristian; Xu, Xiang Ming; Ruoff, Peter

      (2012)

      A Basic Set of Homeostatic Controller Motifs.

      Biophysical Journal

      ISSN 0006-3495.

      Volum 103.

      Hefte 9.

      s.2000-2010.

      DOI: 10.1016/j.bpj.2012.09.033

    • Drengstig, Tormod; Ni, Xiaoyu; Thorsen, Kristian; Jolma, Ingunn Westvik; Ruoff, Peter

      (2012)

      Robust Adaptation and Homeostasis by Autocatalysis.

      Journal of Physical Chemistry B

      ISSN 1520-6106.

      Volum 116.

      Hefte 18.

      s.5355-5363.

      DOI: 10.1021/jp3004568

  • Bøker og kapitler
    • Fjeld, Gunhild; Thorsen, Kristian; Nordgård, Oddmund

      (2020)

      A systems biology approach to cellular homeostasis, volume changes and regulation of metabolism.

      Universitetet i Stavanger

      ISBN 978-82-7644-916-7.

      Hefte 509.

    • Tveit, Daniel Myklatun; Thorsen, Kristian; Drengstig, Tormod; Ruoff, Peter

      (2020)

      Structural Properties of Biological Integral Feedback Motifs.

      Universitetet i Stavanger

      ISBN 978-82-7644-951-8.

      Hefte 544.

    • Thorsen, Kristian; Drengstig, Tormod; Ruoff, Peter

      (2015)

      Controller Motifs for Homeostatic Regulation and Their Applications in Biological Systems.

      Universitetet i Stavanger

      ISBN 978-82-7644-628-9.

      Hefte 276.

  • Formidling
    • Thorsen, Kristian

      (2020)

      The WastewaterAMR Project - Spread of Antibiotic Resistance in Wastewater Treatment Plants.

    • Thorsen, Kristian; Kommedal, Roald; Lood, Rolf

      (2020)

      Wastewater treatment plants as critical reservoirs for resistance genes - Summary of JPI-EC-AMR JTC 2016 project: Gene-gas .

    • Thorsen, Kristian; Davidson, Matthew

      (2020)

      Wastewater-AMR -- et partnerprosjekt i Senter for Digitalt Liv Norge.

    • Thorsen, Kristian; Grønnestad, Kjetil S.; Braut, Knut; Øien, Stian

      (2020)

      Lade-naboene kjemper om Elbil Markedet.

    • Uluseker, Cansu; Kaster, Krista Michelle; Thorsen, Kristian; Kommedal, Roald

      (2019)

      Modeling Antimicrobial Resistance Gene Transfer in Wastewater Treatment Plants.

    • Uluseker, Cansu; Kaster, Krista Michelle; Thorsen, Kristian; Kommedal, Roald

      (2019)

      Mechanism of Antibiotic Resistance Gene Spread in Wastewater Treatment Plants Using Activated Sludge.

    • Thorsen, Kristian

      (2019)

      Mathematical modeling of biological processes and biological cybernetics.

    • Thorsen, Kristian

      (2019)

      Principles for feedback and control in biological systems. And a controller for increased copper tolerance in yeast.

    • Thorsen, Kristian

      (2019)

      Mathematical foundations for industrial robots.

    • Tveit, Daniel Myklatun; Thorsen, Kristian; Drengstig, Tormod

      (2019)

      Modeling regulatory mechanisms behind sustained glucose uptake in growing cancer cells.

    • Løvås, Mari; Thorsen, Kristian

      (2019)

      Teknologiaften - How to motivate and inspire girls to a career in STEM fields?.

    • Uluseker, Cansu; Basiry, Daniel; Stokka, Svein Håvard; Kaster, Krista Michelle; Thorsen, Kristian; Kommedal, Roald

      (2019)

      Modelling Antibiotic Resistance Gene Spread in Wastewater Treatment Plants.

    • Uluseker, Cansu; Basiry, Daniel; Stokka, Svein Håvard; Kaster, Krista Michelle; Thorsen, Kristian; Kommedal, Roald

      (2019)

      Modelling Antibiotic Resistance Gene Spread in Wastewater Treatment Plants.

    • Kommedal, Roald; Kumar, Gopalakrishnan; Kaster, Krista Michelle; Pala Ozkok, Ilke; Thorsen, Kristian

      (2018)

      A simple mathematical model for antimicrobial resistance gene transfer in wastewater treatment models.

    • Fjeld, Gunhild; Nordgård, Oddmund; Thorsen, Kristian

      (2018)

      Combining real time experimental data with a mathematical model to understand cancer cell metabolism.

    • Fjeld, Gunhild; Nordgård, Oddmund; Thorsen, Kristian

      (2018)

      Modeling the redirection of metabolic flux in cancer cells.

    • Ang, Jordan; Tveit, Daniel Myklatun; Fjeld, Gunhild; Drengstig, Tormod; Ruoff, Heinz Peter; McMillen, David R.; Thorsen, Kristian

      (2018)

      Reconciling principles for how to achieve feedback and control in biological systems.

    • Thorsen, Kristian

      (2018)

      Mathematical foundations for industrial robots.

    • Thorsen, Kristian

      (2018)

      How to achieve and understand feedback and control in biological systems.

    • Thorsen, Kristian

      (2018)

      Work at the UiS group for biological cybernetics: Building a controller for regulation of intracellular copper in yeast..

    • Stokka, Svein H.; Jakobsen, Kim A.; Thorsen, Kristian; Drengstig, Tormod

      (2017)

      Physiological based Modeling and Control of an Industrial Tank Process.

    • Tveit, Daniel Myklatun; Thorsen, Kristian

      (2017)

      Passivity-based analysis of biochemical networks displaying homeostasis.

    • Thorsen, Kristian

      (2016)

      Kaosteori - deterministiske system med uventet og irregulær oppførsel..

    • Thorsen, Kristian; Risvoll, Geir; Tveit, Daniel Myklatun; Ruoff, Peter; Drengstig, Tormod

      (2016)

      Tuning of Physiological Controller Motifs.

    • Thorsen, Kristian; Risvoll, Geir; Mazumder, Mostafizur; McMillen, David R.

      (2016)

      A controller for regulation of intracellular copper in S. cerevisiae.

    • Thorsen, Kristian

      (2016)

      The tendency against change: control and regulation as a condition for life..

    • Thorsen, Kristian

      (2015)

      Building controller motifs to manipulate copper tolerance and homeostasis in S. cerevisiae..

    • Thorsen, Kristian; Taraldsen, Lars; Andersen, Ina

      (2015)

      Automatisering - De mest utsatte ingeniørene: Derfor frykter de ikke automatiseringen.

    • Agafonov, Oleg; Selstø, Christina Helen; Thorsen, Kristian; Xu, Xiang Ming; Drengstig, Tormod; Ruoff, Peter

      (2015)

      The Organization of Controller Motifs Leading to Robust Plant Iron Homeostasis.

    • Thorsen, Kristian; Drengstig, Tormod; Ruoff, Peter; Gundersen, Ina

      (2015)

      Nytt sykehus Ullandhaug - Jubler for plasseringen.

    • Thorsen, Kristian; Drengstig, Tormod; Ruoff, Peter

      (2013)

      Integrative modeling of glucose transport and homeostasis in enterocytes.

    • Drengstig, Tormod; Jolma, Ingunn Westvik; Thorsen, Kristian; Ruoff, Peter

      (2013)

      Fysiologiske reguleringsmekanismer.

      Naturen

      ISSN 0028-0887.

      Volum 137.

      Hefte 4.

      s.128-137.

    • Thorsen, Kristian

      (2013)

      Kybernetikk og fysiologi - biokjemiske kontrollere.

    • Thorsen, Kristian; Drengstig, Tormod; Ruoff, Peter

      (2012)

      Modeling and simulation of intestinal nutrient uptake.

    • Thorsen, Kristian

      (2012)

      Cybernetics and physiology.

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