Federico Fenaroli

Andrew M. Thompson; Nils-Jørgen Dal; Francesca Boldrin; Noelia Alonso Rodriguez; Gabriela Schäfer; Kerstin Johann; Martin Tobias Speth; Laura Cioetto-Mazzabò; Adrián Pál; Jana Korduláková; Matthias Barz; Federico Fenaroli; William A. Denny; Gareth Wyn Griffiths (2026) New antitubercular pretomanid analogues as potent payloads in polymeric micelles: Leveraging zebrafish assays to accelerate lead optimisation. I: European Journal of Medicinal Chemistry. ISSN 0223-5234. Volum 307. DOI: 10.1016/j.ejmech.2026.118622

Federico Fenaroli; Anna Griego (2025) Pre-clinical characterisation : Which animal model is best for infection?. I: Alessandro Poma; Loris Rizzello, Nanotechnology tools for infection control : Scanning new horizons on next-generation therapies to eradicate pathogens and fight drug resistance. Elsevier. ISBN 9780128239940. s.281-298. DOI: 10.1016/B978-0-12-823994-0.00005-0

Gabriela Schäfer; Dongdong Bi; Federico Fenaroli; Andrew M. Thompson; Anno Saris; Matthias Barz (2024) Nanoparticles Combining Host-Directed Therapeutics and Antibiotics to Boost Bacterial Killing and Overall Survival of Zebrafish Embryos Infected with Mycobacterium Marinum. I: Advanced therapeutics. Online ISSN 2366-3987. DOI: 10.1002/adtp.202400174

Madhavi Bhandari; Héctor Soria-Carrera; Jens Wohlmann; Nils-Jørgen Dal; Jesús M. de la Fuente; Rafael Martín-Rapún; Gareth Wyn Griffiths; Federico Fenaroli (2023) Subcellular localization and therapeutic efficacy of polymeric micellar nanoparticles encapsulating bedaquiline for tuberculosis treatment in zebrafish. I: Biomaterials Science. ISSN 2047-4830. Volum 11. s.2103-2114. DOI: 10.1039/d2bm01835g

Tobias A. Bauer; Jonas Schramm; Federico Fenaroli; Svenja Siemer; Christine I. Seidl; Christine Rosenauer; Regina Bleul; Roland H. Stauber; Kaloian Koynov; Michael Maskos; Matthias Barz (2023) Complex Structures Made Simple – Continuous Flow Production of Core Cross-Linked Polymeric Micelles for Paclitaxel Pro-Drug-Delivery. I: Advanced Materials. ISSN 0935-9648. Volum 35. s.1-9. DOI: 10.1002/adma.202210704

Nils-Jørgen Dal; Gabriela Schäfer; Andrew Thompson; Sascha Schmitt; Natalja Redinger; Noelia Alonso Rodriguez; Kerstin Johann; Jessica Ojong; Jens Wohlmann; Andreas Best; Kaloian Koynov; Rudolf Zentel; Ulrich E. Schaible; Gareth Wyn Griffiths; Matthias Barz; Federico Fenaroli (2023) Π-Π interactions stabilize PeptoMicelle-based formulations of Pretomanid derivatives leading to promising therapy against tuberculosis in zebrafish and mouse models. I: Journal of Controlled Release. ISSN 0168-3659. Volum 354. s.851-868. DOI: 10.1016/j.jconrel.2023.01.037

Adam Creamer; Alessandra Lo Fiego; Alice Agliano; Lino Prados-Martin; Håkon Høgset; Adrian Najer; Daniel A. Richards; Jonathan P. Wojciechowski; James E. J. Foote; Nayoung Kim; Amy Monahan; Jiaqing Tang; André Shamsabadi; Léa N. C. Rochet; Ioanna A. Thanasi; Laura R de la Ballina; Charlotte L. Rapley; Stephen Turnock; Elizabeth A. Love; Laurence Bugeon; Margaret J. Dallman; Martin Heeney; Gabriela Kramer-Marek; Vijay Chudasama; Federico Fenaroli; Molly M. Stevens (2023) Modular Synthesis of Semiconducting Graft Copolymers to Achieve “Clickable” Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting. I: Advanced Materials. ISSN 0935-9648. DOI: 10.1002/adma.202300413

Christian Czysch; Carolina Medina-Montano; Nils-Jørgen Knudsen Dal; Thi Dinh; Yannick Fröder; Pia Winterwerber; Konrad Maxeiner; Hans-Joachim Räder; Detlef Schuppan; Hansjörg Schild; Matthias Bros; Bernhard Biersack; Federico Fenaroli; Stephan Grabbe; Lutz Nuhn (2022) End group dye-labeled polycarbonate block copolymers for micellar (immuno-)drug delivery. I: Macromolecular rapid communications. ISSN 1022-1336. Volum 43. s.1-10. DOI: 10.1002/marc.202200095

Jiří Trousil; Nils-Jørgen Dal; Federico Fenaroli; Inbar Schlachet; Pavla Kubíčková; Olga Janoušková; Ewa Pavlova; Miša Škorič; Kateřina Trejbalová; Oto Pavliš; Alejandro Sosnik (2022) Antibiotic-Loaded Amphiphilic Chitosan Nanoparticles Target Macrophages and Kill an Intracellular Pathogen. I: Small. ISSN 1613-6810. Volum 18. DOI: 10.1002/smll.202201853

Adrian Najer; Alexis Belessiotis-Richards; Hyemin Kim; Catherine Saunders; Federico Fenaroli; Christopher Adrianus; Junyi Che; Renée L. Tonkin; Håkon Høgset; Samuel Lörcher; Matthew Penna; Stuart G. Higgins; Wolfgang Meier; Irene Yarovsky; Molly M. Stevens (2022) Block Length-Dependent Protein Fouling on Poly(2-oxazoline)-Based Polymersomes: Influence on Macrophage Association and Circulation Behavior. I: Small. ISSN 1613-6810. Volum 18. DOI: 10.1002/smll.202201993

Ghada Bouz; Petr Šlechta; Ondřej Jand'ourek; Klára Konečná; Pavla Paterová; Pavel Bárta; Martin Novák; Radim Kučera; Nils-Jørgen Dal; Federico Fenaroli; Júlia Zemanová; Martin Forbak; Jana Korduláková; Oto Pavliš; Pavla Kubíčková; Martin Doležal; Jan Zitko (2022) Hybridization Approach Toward Novel Antituberculars: Design, Synthesis, and Biological Evaluation of Compounds Combining Pyrazinamide and 4-Aminosalicylic Acid. I: ACS Infectious Diseases. Online ISSN 2373-8227. Volum 9. s.79-96. DOI: 10.1021/acsinfecdis.2c00433

Nils-Jørgen Knudsen Dal; Martin Tobias Speth; Kerstin Johann; Matthias Barz; Claire Beauvineau; Jens Wohlmann; Federico Fenaroli; Brigitte Gicquel; Gareth Wyn Griffiths; Noelia Alonso Rodriguez (2022) The zebrafish embryo as an in vivo model for screening nanoparticle-formulated lipophilic anti-tuberculosis compounds. I: Disease Models and Mechanisms. ISSN 1754-8403. Volum 15. DOI: 10.1242/dmm.049147

Svenja Siemer; Tobias A. Bauer; Paul Scholz; Christina Breder; Federico Fenaroli; Gregory Harms; Dimo Dietrich; Jörn Dietrich; Christine Rosenauer; Matthias Barz; Sven Becker; Sebastian Strieth; Christoph Reinhardt; Torsten Fauth; Jan Hagemann; Roland H. Stauber (2021) Targeting Cancer Chemotherapy Resistance by Precision Medicine-Driven Nanoparticle-Formulated Cisplatin. I: ACS Nano. ISSN 1936-0851. Volum 15. s.18541-18556. DOI: 10.1021/acsnano.1c08632

Tobias A. Bauer; Natalie K. Horvat; Oriana Marques; Sara Chocarro; Christina Mertens; Silvia Colucci; Sascha Schmitt; Luca M. Carrella; Svenja Morsbach; Kaloian Koynov; Federico Fenaroli; Peter Blümler; Michaela Jung; Rocio Sotillo; Matthias W. Hentze; Martina Muckenthaler; Matthias Barz (2021) Core Cross-Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages. I: Advanced Healthcare Materials. ISSN 2192-2640. Volum 10. s.1-13. DOI: 10.1002/adhm.202100385

Julien Resseguier; Jean-Pierre Levraud; Nils-Jørgen Knudsen Dal; Federico Fenaroli; Charlotte Primard; Jens Wohlmann; Gabrielle Carron; Gareth Wyn Griffiths; Dominique Le Guellec; Bernard Verrier (2021) Biodistribution of surfactant-free poly(lactic-acid) nanoparticles and uptake by endothelial cells and phagocytes in zebrafish: Evidence for endothelium to macrophage transfer. I: Journal of Controlled Release. ISSN 0168-3659. Volum 331. s.228-245. DOI: 10.1016/j.jconrel.2021.01.006

Agnese Kocere; Julien Resseguier; Jens Wohlmann; Frode Miltzow Skjeldal; Shanawaz Khan; Martin Speth; Nils-Jørgen Knudsen Dal; Matthew Yoke Wui Ng; Noelia Alonso Rodriguez; Edoardo Scarpa; Loris Rizzello; Giuseppe Battaglia; Gareth Wyn Griffiths; Federico Fenaroli (2020) Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. I: EBioMedicine. Online ISSN 2352-3964. Volum 58. s.1-12. DOI: 10.1016/j.ebiom.2020.102902

Federico Fenaroli; James Robertson; Edoardo Scarpa; Virginia Gouveia; Claudia Di Guglielmo; Cesare De Pace; Philip Elks; Alessandro Poma; Dimitrios Evangelopoulos; Ortiz Canseco Julio; Tomasz Prajsnar; Helen Marriott; David Dockrell; Simon J Foster; Timothy McHugh; Stephen Renshaw; Josep Samiter Marti; Giuseppe Battaglia; Loris Rizzello (2020) Polymersomes Eradicating Intracellular Bacteria. I: ACS Nano. ISSN 1936-0851. Volum 14. s.8287-8298. DOI: 10.1021/acsnano.0c01870

Nils-Jørgen Knudsen Dal; Agnese Kocere; Jens Wohlmann; Simon Van Herck; Tobias A Bauer; Julien Resseguier; Shahla Bagheri Fam; Hilde C Bergvin Hyldmo; Matthias Barz; Bruno G. De Geest; Federico Fenaroli (2020) Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle–Cell Interactions. I: Small. ISSN 1613-6810. Volum 16. s.1-12. DOI: 10.1002/smll.201906719

Jiří Trousil; Zdeňka Syrová; Nils-Jørgen Knudsen Dal; Dmytro Rak; Rafal Konefal; Ewa Pavlova; Jana Matejkova; Dusan Cmarko; Pavla Kubickova; Oto Pavlis; Tomáš Urbánek; Marian Sedlak; Federico Fenaroli; Ivan Raška; Petr Stepanek; Martin Hrubý (2019) Rifampicin Nanoformulation Enhances Treatment of Tuberculosis in Zebrafish. I: Biomacromolecules. ISSN 1525-7797. Volum 20. s.1798-1815. DOI: 10.1021/acs.biomac.9b00214

Katharina Vestre; Ingrid Kjos; Noemi Antonella Guadagno; Marita Borg Distefano; Felix Kohler; Federico Fenaroli; Oddmund Bakke; Cinzia Progida (2019) Rab6 regulates cell migration and invasion by recruiting Cdc42 and modulating its activity. I: Cellular and Molecular Life Sciences (CMLS). ISSN 1420-682X. Volum 76. s.2593-2614. DOI: 10.1007/s00018-019-03057-w

Sheemal S. Kumar; Julia Isabel Tandberg; Anahit Penesyan; Liam D. H. Elbourne; Nadia Suarez-Bosche; Emily Don; Eline Supannee Setu Skadberg; Federico Fenaroli; Nicholas Cole; Hanne Cecilie Winther-Larsen; Ian T. Paulsen (2018) Dual Transcriptomics of Host-Pathogen Interaction of Cystic Fibrosis Isolate Pseudomonas aeruginosa PASS1 With Zebrafish. I: Frontiers in Cellular and Infection Microbiology. Online ISSN 2235-2988. DOI: 10.3389/fcimb.2018.00406

Alexandra Van Driessche; Agnese Kocere; Hannelien Everaert; Lutz Nuhn; Simon Van Herck; Gareth Wyn Griffiths; Federico Fenaroli; Bruno G. De Geest (2018) pH-sensitive hydrazone-linked doxorubicin nanogels via polymeric-activated ester scaffolds: Synthesis, assembly, and in vitro and in vivo evaluation in tumor-bearing zebrafish. I: Chemistry of Materials. ISSN 0897-4756. Volum 30. s.8587-8596. DOI: 10.1021/acs.chemmater.8b03702

Federico Fenaroli; Urska Repnik; Yitian Xu; Kerstin Johann; Simon Van Herck; Pradip Dey; Frode Miltzow Skjeldal; Dominik Michael Frei; Shahla Bagheri Fam; Agnese Kocere; Rainer Haag; Bruno G. De Geest; Matthias Barz; David G. Russell; Gareth Wyn Griffiths (2018) Enhanced permeability and retention-like extravasation of nanoparticles from the vasculature into tuberculosis granulomas in zebrafish and mouse models. I: ACS Nano. ISSN 1936-0851. Volum 12. s.8646-8661. DOI: 10.1021/acsnano.8b04433

Lilia Ulanova; Marina Pinheiro; Carina Beatrice Vibe; Clàudia Nunes; Dorna Misaghian; Steven Ray Haakon Wilson; Kaizheng Zhu; Federico Fenaroli; Hanne Cecilie Winther-Larsen; Saletta Reis; Gareth Griffiths (2017) Treatment of Francisella infections via PLGA-and lipid-based nanoparticle delivery of antibiotics in a zebrafish model. I: Diseases of Aquatic Organisms. ISSN 0177-5103. Volum 125. s.19-29. DOI: 10.3354/dao03129

Patrick Lie Johansen; Federico Fenaroli; Lasse Evensen; Gareth Griffiths; Gerbrand Koster (2016) Optical micromanipulation of nanoparticles and cells inside living zebrafish. I: Nature Communications. Online ISSN 2041-1723. Volum 7. DOI: 10.1038/ncomms10974

Carina Beatrice Vibe; Federico Fenaroli; David Pires; Steven Ray Haakon Wilson; Vanya Bogoeva; Raja Sab Kalluru; Martin Speth; Elsa Anes; Gareth Griffiths; Jon Paul Hildahl (2016) Thioridazine in PLGA nanoparticles reduces toxicity and improves rifampicin therapy against mycobacterial infection in zebrafish. I: Nanotoxicology. ISSN 1743-5390. Volum 10. s.680-688. DOI: 10.3109/17435390.2015.1107146

Lasse Evensen; Patrick Lie Johansen; Gerbrand Koster; Kaizheng Zhu; Lars Herfindal; Martin Speth; Federico Fenaroli; Jon Paul Hildahl; Shahla Bagheri Fam; Claudia Tulotta; Lina Prasmickaite; Gunhild Mælandsmo; Ewa Snaar-Jagalska; Gareth Wyn Griffiths (2016) Zebrafish as a model system for characterization of nanoparticles against cancer. I: Nanoscale. ISSN 2040-3364. Volum 8. s.862-877. DOI: 10.1039/c5nr07289a

Meric Erikci Ertunc; Jørgen Sikkeland; Federico Fenaroli; Gareth Wyn Griffiths; Melissa C. Daniels; Haiming Cao; Fahri Saatcioglu; Gökhan S. Hotamisligil (2015) Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity. I: Journal of Lipid Research. ISSN 0022-2275. Volum 56. s.423-434. DOI: 10.1194/jlr.M055798

Federico Fenaroli; David Westmoreland; Jørgen Benjaminsen; Terje R Selnes Kolstad; Frode Miltzow Skjeldal; Annemarie H. Meijer; Michiel van der Vaart; Lilia Ulanova; Norbert Roos; Bo Nyström; Jon Paul Hildahl; Gareth Wyn Griffiths (2014) Nanoparticles as Drug Delivery System against Tuberculosis in Zebrafish Embryos: Direct Visualization and Treatment. I: ACS Nano. ISSN 1936-0851. Volum 8. s.7014-7026. DOI: 10.1021/nn5019126

Raja Sab Kalluru; Federico Fenaroli; David Westmoreland; Lilia Ulanova; Atoosa Maleki; Norbert Roos; Marie Paulsen Madsen; Gerbrand Koster; Wolfgang Mathias Jacobsen; Steven Ray Haakon Wilson; Hanne Røberg-Larsen; Gopal K. Khuller; Amandeep Singh; Bo Nyström; Gareth Wyn Griffiths (2013) Polylactide-co-glycolide-rifampicin-nanoparticles efficiently clear Mycobacterium bovis BCG infection in macrophages and remain membrane-bound in phago-lysosomes. I: Journal of Cell Science. ISSN 0021-9533. Volum 126. s.3043-3054. DOI: 10.1242/jcs.121814

Lesniak Anna; Federico Fenaroli; Marco Monopoli; Christoffer Åberg; Kenneth A. Dawson; Anna Salvati (2012) Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells. I: ACS Nano. ISSN 1936-0851. Volum 6. s.5845-5857. DOI: 10.1021/nn300223w

Mariana Bexiga; Juan Varela; Fengjuan Wang; Federico Fenaroli; Anna Salvati; Iseult Lynch; Jeremy Simpson; Kenneth A. Dawson (2011) Cationic nanoparticles induce caspase 3-, 7- and 9-mediated cytotoxicity in a human astrocytoma cell line. I: Nanotoxicology. ISSN 1743-5390. Volum 5. s.557-567. DOI: 10.3109/17435390.2010.539713

Kayle Shapero; Federico Fenaroli; Iseult Lynch; David Cottell; Anna Salvati; Kenneth A. Dawson (2011) Time and space resolved uptake study of silica nanoparticles by human cells. I: Molecular Biosystems. ISSN 1742-206X. Volum 7. s.371-378. DOI: 10.1039/c0mb00109k