Førsteamanuensis i biologisk kjemi
Dal, Nils-Jørgen; Schäfer, Gabriela; Thompson, Andrew; Schmitt, Sascha; Redinger, Natalja; Alonso Rodriguez, Noelia; Johann, Kerstin; Ojong, Jessica; Wohlmann, Jens; Best, Andreas; Koynov, Kaloian; Zentel, Rudolf; Schaible, Ulrich E.; Griffiths, Gareth Wyn; Barz, Matthias; Fenaroli, Federico
(2023)
Π-Π interactions stabilize PeptoMicelle-based formulations of Pretomanid derivatives leading to promising therapy against tuberculosis in zebrafish and mouse models.Journal of Controlled Release.
ISSN 0168-3659.
Volum 354.
s.851-868.
Bhandari, Madhavi; Soria-Carrera, Héctor; Wohlmann, Jens; Dal, Nils-Jørgen; de la Fuente, Jesús M.; Martín-Rapún, Rafael; Griffiths, Gareth Wyn; Fenaroli, Federico
(2023)
Subcellular localization and therapeutic efficacy of polymeric micellar nanoparticles encapsulating bedaquiline for tuberculosis treatment in zebrafish.Biomaterials Science.
ISSN 2047-4830.
Volum 11.
Hefte 6.
s.2103-2114.
DOI: 10.1039/d2bm01835
Creamer, Adam; Fiego, Alessandra Lo; Agliano, Alice; Prados-Martin, Lino; Høgset, Håkon; Najer, Adrian; Richards, Daniel A.; Wojciechowski, Jonathan P.; Foote, James E. J.; Kim, Nayoung; Monahan, Amy; Tang, Jiaqing; Shamsabadi, André; Rochet, Léa N. C.; Thanasi, Ioanna A.; de la Ballina, Laura R; Rapley, Charlotte L.; Turnock, Stephen; Love, Elizabeth A.; Bugeon, Laurence; Dallman, Margaret J.; Heeney, Martin; Kramer-Marek, Gabriela; Chudasama, Vijay; Fenaroli, Federico; Stevens, Molly M.
(2023)
Modular Synthesis of Semiconducting Graft Copolymers to Achieve “Clickable” Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting.Advanced Materials.
ISSN 0935-9648.
Bauer, Tobias A.; Schramm, Jonas; Fenaroli, Federico; Siemer, Svenja; Seidl, Christine I.; Rosenauer, Christine; Bleul, Regina; Stauber, Roland H.; Koynov, Kaloian; Maskos, Michael; Barz, Matthias
(2023)
Complex Structures Made Simple – Continuous Flow Production of Core Cross-Linked Polymeric Micelles for Paclitaxel Pro-Drug-Delivery.Advanced Materials.
ISSN 0935-9648.
Volum 35.
Hefte 21.
s.1-9.
Dal, Nils-Jørgen Knudsen; Speth, Martin Tobias; Johann, Kerstin; Barz, Matthias; Beauvineau, Claire; Wohlmann, Jens; Fenaroli, Federico; Gicquel, Brigitte; Griffiths, Gareth Wyn; Alonso Rodriguez, Noelia
(2022)
The zebrafish embryo as an in vivo model for screening nanoparticle-formulated lipophilic anti-tuberculosis compounds.Disease Models and Mechanisms.
ISSN 1754-8403.
Volum 15.
Hefte 1.
DOI: 10.1242/dmm.049147
Czysch, Christian; Medina-Montano, Carolina; Dal, Nils-Jørgen Knudsen; Dinh, Thi; Fröder, Yannick; Winterwerber, Pia; Maxeiner, Konrad; Räder, Hans-Joachim; Schuppan, Detlef; Schild, Hansjörg; Bros, Matthias; Biersack, Bernhard; Fenaroli, Federico; Grabbe, Stephan; Nuhn, Lutz
(2022)
End group dye-labeled polycarbonate block copolymers for micellar (immuno-)drug delivery.Macromolecular rapid communications.
ISSN 1022-1336.
Volum 43.
Hefte 12.
s.1-10.
Najer, Adrian; Belessiotis-Richards, Alexis; Kim, Hyemin; Saunders, Catherine; Fenaroli, Federico; Adrianus, Christopher; Che, Junyi; Tonkin, Renée L.; Høgset, Håkon; Lörcher, Samuel; Penna, Matthew; Higgins, Stuart G.; Meier, Wolfgang; Yarovsky, Irene; Stevens, Molly M.
(2022)
Block Length-Dependent Protein Fouling on Poly(2-oxazoline)-Based Polymersomes: Influence on Macrophage Association and Circulation Behavior.Small.
ISSN 1613-6810.
Volum 18.
Hefte 27.
Trousil, Jiří; Dal, Nils-Jørgen; Fenaroli, Federico; Schlachet, Inbar; Kubíčková, Pavla; Janoušková, Olga; Pavlova, Ewa; Škorič, Miša; Trejbalová, Kateřina; Pavliš, Oto; Sosnik, Alejandro
(2022)
Antibiotic-Loaded Amphiphilic Chitosan Nanoparticles Target Macrophages and Kill an Intracellular Pathogen.Small.
ISSN 1613-6810.
Volum 18.
Hefte 28.
Bouz, Ghada; Šlechta, Petr; Jand'ourek, Ondřej; Konečná, Klára; Paterová, Pavla; Bárta, Pavel; Novák, Martin; Kučera, Radim; Dal, Nils-Jørgen; Fenaroli, Federico; Zemanová, Júlia; Forbak, Martin; Korduláková, Jana; Pavliš, Oto; Kubíčková, Pavla; Doležal, Martin; Zitko, Jan
(2022)
Hybridization Approach Toward Novel Antituberculars: Design, Synthesis, and Biological Evaluation of Compounds Combining Pyrazinamide and 4-Aminosalicylic Acid.ACS Infectious Diseases.
ISSN 2373-8227.
Volum 9.
Hefte 1.
s.79-96.
Resseguier, Julien; Levraud, Jean-Pierre; Dal, Nils-Jørgen Knudsen; Fenaroli, Federico; Primard, Charlotte; Wohlmann, Jens; Carron, Gabrielle; Griffiths, Gareth Wyn; Le Guellec, Dominique; Verrier, Bernard
(2021)
Biodistribution of surfactant-free poly(lactic-acid) nanoparticles and uptake by endothelial cells and phagocytes in zebrafish: Evidence for endothelium to macrophage transfer.Journal of Controlled Release.
ISSN 0168-3659.
Volum 331.
s.228-245.
Siemer, Svenja; Bauer, Tobias A.; Scholz, Paul; Breder, Christina; Fenaroli, Federico; Harms, Gregory; Dietrich, Dimo; Dietrich, Jörn; Rosenauer, Christine; Barz, Matthias; Becker, Sven; Strieth, Sebastian; Reinhardt, Christoph; Fauth, Torsten; Hagemann, Jan; Stauber, Roland H.
(2021)
Targeting Cancer Chemotherapy Resistance by Precision Medicine-Driven Nanoparticle-Formulated Cisplatin.ACS Nano.
ISSN 1936-0851.
Volum 15.
Hefte 11.
s.18541-18556.
Bauer, Tobias A.; Horvat, Natalie K.; Marques, Oriana; Chocarro, Sara; Mertens, Christina; Colucci, Silvia; Schmitt, Sascha; Carrella, Luca M.; Morsbach, Svenja; Koynov, Kaloian; Fenaroli, Federico; Blümler, Peter; Jung, Michaela; Sotillo, Rocio; Hentze, Matthias W.; Muckenthaler, Martina; Barz, Matthias
(2021)
Core Cross-Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages.Advanced Healthcare Materials.
ISSN 2192-2640.
Volum 10.
Hefte 19.
s.1-13.
Dal, Nils-Jørgen Knudsen; Kocere, Agnese; Wohlmann, Jens; Van Herck, Simon; Bauer, Tobias A; Resseguier, Julien; Bagheri Fam, Shahla; Hyldmo, Hilde C Bergvin; Barz, Matthias; De Geest, Bruno G.; Fenaroli, Federico
(2020)
Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle–Cell Interactions.Small.
ISSN 1613-6810.
Volum 16.
Hefte 5.
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Kocere, Agnese; Resseguier, Julien; Wohlmann, Jens; Skjeldal, Frode Miltzow; Khan, Shanawaz; Speth, Martin; Dal, Nils-Jørgen Knudsen; Ng, Matthew Yoke Wui; Alonso Rodriguez, Noelia; Scarpa, Edoardo; Rizzello, Loris; Battaglia, Giuseppe; Griffiths, Gareth Wyn; Fenaroli, Federico
(2020)
Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis.EBioMedicine.
ISSN 2352-3964.
Volum 58.
s.1-12.
Fenaroli, Federico; Robertson, James; Scarpa, Edoardo; Gouveia, Virginia; Di Guglielmo, Claudia; De Pace, Cesare; Elks, Philip; Poma, Alessandro; Evangelopoulos, Dimitrios; Julio, Ortiz Canseco; Prajsnar, Tomasz; Marriott, Helen; Dockrell, David; Foster, Simon J; McHugh, Timothy; Renshaw, Stephen; Samiter Marti, Josep; Battaglia, Giuseppe; Rizzello, Loris
(2020)
Polymersomes Eradicating Intracellular Bacteria.ACS Nano.
ISSN 1936-0851.
Volum 14.
Hefte 7.
s.8287-8298.
Vestre, Katharina; Kjos, Ingrid; Guadagno, Noemi Antonella; Distefano, Marita Borg; Kohler, Felix; Fenaroli, Federico; Bakke, Oddmund; Progida, Cinzia
(2019)
Rab6 regulates cell migration and invasion by recruiting Cdc42 and modulating its activity.Cellular and Molecular Life Sciences (CMLS).
ISSN 1420-682X.
Volum 76.
Hefte 13.
s.2593-2614.
Trousil, Jiří; Syrová, Zdeňka; Dal, Nils-Jørgen Knudsen; Rak, Dmytro; Konefal, Rafal; Pavlova, Ewa; Matejkova, Jana; Cmarko, Dusan; Kubickova, Pavla; Pavlis, Oto; Urbánek, Tomáš; Sedlak, Marian; Fenaroli, Federico; Raška, Ivan; Stepanek, Petr; Hrubý, Martin
(2019)
Rifampicin Nanoformulation Enhances Treatment of Tuberculosis in Zebrafish.Biomacromolecules.
ISSN 1525-7797.
Volum 20.
Hefte 4.
s.1798-1815.
Fenaroli, Federico; Repnik, Urska; Xu, Yitian; Johann, Kerstin; Van Herck, Simon; Dey, Pradip; Skjeldal, Frode Miltzow; Frei, Dominik Michael; Fam, Shahla Bagheri; Kocere, Agnese; Haag, Rainer; De Geest, Bruno G.; Barz, Matthias; Russell, David G.; Griffiths, Gareth Wyn
(2018)
Enhanced permeability and retention-like extravasation of nanoparticles from the vasculature into tuberculosis granulomas in zebrafish and mouse models.ACS Nano.
ISSN 1936-0851.
Volum 12.
Hefte 8.
s.8646-8661.
Van Driessche, Alexandra; Kocere, Agnese; Everaert, Hannelien; Nuhn, Lutz; Van Herck, Simon; Griffiths, Gareth Wyn; Fenaroli, Federico; De Geest, Bruno G.
(2018)
pH-sensitive hydrazone-linked doxorubicin nanogels via polymeric-activated ester scaffolds: Synthesis, assembly, and in vitro and in vivo evaluation in tumor-bearing zebrafish.Chemistry of Materials.
ISSN 0897-4756.
Volum 30.
Hefte 23.
s.8587-8596.
Kumar, Sheemal S.; Tandberg, Julia Isabel; Penesyan, Anahit; Elbourne, Liam D. H.; Suarez-Bosche, Nadia; Don, Emily; Skadberg, Eline Supannee Setu; Fenaroli, Federico; Cole, Nicholas; Winther-Larsen, Hanne Cecilie; Paulsen, Ian T.
(2018)
Dual Transcriptomics of Host-Pathogen Interaction of Cystic Fibrosis Isolate Pseudomonas aeruginosa PASS1 With Zebrafish.Frontiers in Cellular and Infection Microbiology.
ISSN 2235-2988.
Ulanova, Lilia; Pinheiro, Marina; Vibe, Carina Beatrice; Nunes, Clàudia; Misaghian, Dorna; Wilson, Steven Ray Haakon; Zhu, Kaizheng; Fenaroli, Federico; Winther-Larsen, Hanne Cecilie; Reis, Saletta; Griffiths, Gareth
(2017)
Treatment of Francisella infections via PLGA-and lipid-based nanoparticle delivery of antibiotics in a zebrafish model.Diseases of Aquatic Organisms.
ISSN 0177-5103.
Volum 125.
Hefte 1.
s.19-29.
DOI: 10.3354/dao03129
Evensen, Lasse; Lie Johansen, Patrick; Koster, Gerbrand; Zhu, Kaizheng; Herfindal, Lars; Speth, Martin; Fenaroli, Federico; Hildahl, Jon Paul; Fam, Shahla Bagheri; Tulotta, Claudia; Prasmickaite, Lina; Mælandsmo, Gunhild; Snaar-Jagalska, Ewa; Griffiths, Gareth Wyn
(2016)
Zebrafish as a model system for characterization of nanoparticles against cancer.Nanoscale.
ISSN 2040-3364.
Volum 8.
Hefte 2.
s.862-877.
DOI: 10.1039/c5nr07289a
Vibe, Carina Beatrice; Fenaroli, Federico; Pires, David; Wilson, Steven Ray Haakon; Bogoeva, Vanya; Kalluru, Raja Sab; Speth, Martin; Anes, Elsa; Griffiths, Gareth; Hildahl, Jon Paul
(2016)
Thioridazine in PLGA nanoparticles reduces toxicity and improves rifampicin therapy against mycobacterial infection in zebrafish.Nanotoxicology.
ISSN 1743-5390.
Volum 10.
Hefte 6.
s.680-688.
Lie Johansen, Patrick; Fenaroli, Federico; Evensen, Lasse; Griffiths, Gareth; Koster, Gerbrand
(2016)
Optical micromanipulation of nanoparticles and cells inside living zebrafish.Nature Communications.
ISSN 2041-1723.
Volum 7.
DOI: 10.1038/ncomms10974
Ertunc, Meric Erikci; Sikkeland, Jørgen; Fenaroli, Federico; Griffiths, Gareth Wyn; Daniels, Melissa C.; Cao, Haiming; Saatcioglu, Fahri; Hotamisligil, Gökhan S.
(2015)
Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity.Journal of Lipid Research.
ISSN 0022-2275.
Volum 56.
Hefte 2.
s.423-434.
DOI: 10.1194/jlr.M055798
Fenaroli, Federico; Westmoreland, David; Benjaminsen, Jørgen; Kolstad, Terje R Selnes; Skjeldal, Frode Miltzow; Meijer, Annemarie H.; van der Vaart, Michiel; Ulanova, Lilia; Roos, Norbert; Nyström, Bo; Hildahl, Jon Paul; Griffiths, Gareth Wyn
(2014)
Nanoparticles as Drug Delivery System against Tuberculosis in Zebrafish Embryos: Direct Visualization and Treatment.ACS Nano.
ISSN 1936-0851.
Volum 8.
Hefte 7.
s.7014-7026.
DOI: 10.1021/nn5019126
Kalluru, Raja Sab; Fenaroli, Federico; Westmoreland, David; Ulanova, Lilia; Maleki, Atoosa; Roos, Norbert; Madsen, Marie Paulsen; Koster, Gerbrand; Jacobsen, Wolfgang Mathias; Wilson, Steven Ray Haakon; Røberg-Larsen, Hanne; Khuller, Gopal K.; Singh, Amandeep; Nyström, Bo; Griffiths, Gareth Wyn
(2013)
Polylactide-co-glycolide-rifampicin-nanoparticles efficiently clear Mycobacterium bovis BCG infection in macrophages and remain membrane-bound in phago-lysosomes.Journal of Cell Science.
ISSN 0021-9533.
Volum 126.
Hefte 14.
s.3043-3054.
DOI: 10.1242/jcs.121814
Anna, Lesniak; Fenaroli, Federico; Monopoli, Marco; Åberg, Christoffer; Dawson, Kenneth A.; Salvati, Anna
(2012)
Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells.ACS Nano.
ISSN 1936-0851.
Volum 6.
Hefte 7.
s.5845-5857.
DOI: 10.1021/nn300223w
Shapero, Kayle; Fenaroli, Federico; Lynch, Iseult; Cottell, David; Salvati, Anna; Dawson, Kenneth A.
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Time and space resolved uptake study of silica nanoparticles by human cells.Molecular Biosystems.
ISSN 1742-206X.
Volum 7.
Hefte 2.
s.371-378.
DOI: 10.1039/c0mb00109k
Bexiga, Mariana; Varela, Juan; Wang, Fengjuan; Fenaroli, Federico; Salvati, Anna; Lynch, Iseult; Simpson, Jeremy; Dawson, Kenneth A.
(2011)
Cationic nanoparticles induce caspase 3-, 7- and 9-mediated cytotoxicity in a human astrocytoma cell line.Nanotoxicology.
ISSN 1743-5390.
Volum 5.
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